6503-22-6

Basic information

• Product Name: Carbamodithioic acid, [(4-methylphenyl)sulfonyl]-, methyl ester
• CAS NO: 6503-22-6
• Molecular Formula: C9H11NO2S3
• Molecular Weight: 261.39
• Mol File: 6503-22-6.mol

Chemical Properties

• CAS DataBase Reference: Carbamodithioic acid, [(4-methylphenyl)sulfonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamodithioic acid, [(4-methylphenyl)sulfonyl]-, methyl ester(6503-22-6)
• EPA Substance Registry System: Carbamodithioic acid, [(4-methylphenyl)sulfonyl]-, methyl ester(6503-22-6)

Safety Data

• Hazardous Substances Data: 6503-22-6(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 74-88-4 methyl iodide 
• 75-15-0 carbon disulfide 

Downstream Products

• 247031-65-8 N-[[(3-methoxyphenyl)amino]thioxomethyl]-4-methylphenylsulfonamide 
• 87840-21-9 4-Methyl-N-[1-methylsulfanyl-1-(2-oxo-2-phenyl-ethylsulfanyl)-meth-(E)-ylidene]-benzenesulfonamide 
• 142011-49-2 diethyl 2-p-toluenesulfonylaminopyrrolo<2,1-a>isoquinoline-1,3-dicarboxylate 
• 142011-53-8 ethyl-1-cyano-2-(p-toluenesulfonylamino)pyrrolo<2,1-a>isoquinoline-3-carboxylate 
• 142011-54-9 methyl 1-cyano-2-(p-toluenesulfonylamino)pyrrolo<2,1-a>isoquinoline-3-carboxylate 
• 86379-83-1 4-Methyl-N-[5-(4-nitro-phenyl)-[1,3]oxathiol-(2E)-ylidene]-benzenesulfonamide 
• 87840-25-3 N-[5-(4-Methoxy-phenyl)-[1,3]oxathiol-(2Z)-ylidene]-4-methyl-benzenesulfonamide 
• 87840-26-4 N-[5-(4-Bromo-phenyl)-[1,3]oxathiol-(2Z)-ylidene]-4-methyl-benzenesulfonamide 
• 87840-24-2 4-Methyl-N-[5-phenyl-[1,3]oxathiol-(2Z)-ylidene]-benzenesulfonamide 
• 142011-46-9 N-(α-cyanomethyl)(α-methylthio)methylene-p-toluenesulfonamide 
• 139458-87-0 S-Methyl-S'-trimethylsilylmethyl N-(p-toluenesulfonyl)dithioiminocarbonate 
• 87840-22-0 N-[1-[2-(4-Methoxy-phenyl)-2-oxo-ethylsulfanyl]-1-methylsulfanyl-meth-(E)-ylidene]-4-methyl-benzenesulfonamide 
• 87840-23-1 N-[1-[2-(4-Bromo-phenyl)-2-oxo-ethylsulfanyl]-1-methylsulfanyl-meth-(E)-ylidene]-4-methyl-benzenesulfonamide 
• 142011-45-8 N-(ethoxycarbonylmethylthio)(methylthio)methylene-p-toluenesulfonamide 

Relevant articles and documents

Synthesis, structural characterization and thromboxane A2 receptor antagonistic activity of 3-substituted 2-[(arylsulfonyl)imino]-2,3- dihydrothiazolyl derivatives

A series of new 2-[(arylsulfonyl)imino]-2,3-dihydrothiazolyl derivatives substituted on the heterocyclic N by a phenoxyacetic moiety was prepared according to a Hantzsch's synthesis between N, N'-disubstituted thioureas and chloroacetaldehyde. The regiochemistry of the cyclocondensation reaction was established by high resolution NMR methods. Potential thromboxane A2/prostaglandin H2 (TxA2/PGH2) receptor antagonism was evaluated using human platelet aggregation assays and radioligand binding studies. The results showed that the affinity for the TxA2/PGH2 receptor was strongly dependent on the position of the oxyacetic acid side chain. On the basis of the X-ray crystal analysis of compound 9f, a molecular modelling was undertaken on compounds 3d, 3e, and 3f. Comparison with the 3D structure of sulotroban was discussed.