65037-44-7Relevant academic research and scientific papers
Nickel/Photo-Cocatalyzed Asymmetric Acyl-Carbamoylation of Alkenes
Fan, Pei,Lan, Yun,Zhang, Chang,Wang, Chuan
, p. 2180 - 2186 (2020/03/03)
An unprecedented asymmetric acyl-carbamoylation of pendant alkenes tethered on aryl carbamic chlorides with both aliphatic and aromatic aldehydes has been developed via the cooperative catalysis of a chiral nickel-PHOX complex and tetrabutylammonium decatungstate. This reaction represents the first example of merging hydrogen-atom-transfer photochemistry and asymmetric transition metal catalysis in difunctionalization of alkenes. Using this protocol, a variety of oxindoles bearing a challenging quaternary stereogenic center are furnished under mild conditions in highly enantioselective manner.
Perfluorobutyl Iodide Mediated [1,2] and [2,3] Stevens Rearrangement for the Synthesis of Indolin-3-Ones
Chen, Zhen-Yu,Lin, Bi-Zhen,Chen, Lei,Zou, Yong,Yan, Ming,Zhang, Xue-Jing
supporting information, p. 4368 - 4372 (2020/09/07)
The tertiary amine and ketone components of 1-carbonyl-substituted anilines undergo [1,2] and [2,3] Stevens rearrangement reactions, triggered by a C4F9 radical, formed from electron donor–acceptor complexes. This approach enables the formation of a quaternary ammonium salt and thus a Stevens rearrangement to afford indolin-3-ones under mild conditions. (Figure presented.).
Copper-catalyzed intramolecular oxidative C(sp3)-H amidation of 2-aminoacetophenones: Efficient synthesis of indoline-2,3-diones
Huang, Jinbo,Mao, Tingting,Zhu, Qiang
supporting information, p. 2878 - 2882 (2014/05/20)
An efficient synthesis of diverse indoline-2,3-diones from 2-aminoacetophenones through copper-catalyzed intramolecular C(sp3)-H amidation is developed. The reaction proceeds in DMSO by using O2 as the sole oxidant to provide the desired products in moderate to good yields.
Synthesis of 4-quinolones through nickel-catalyzed intramolecular amination on the β-carbon of o-(N-alkylamino)propiophenones
Ueno, Satoshi,Shimizu, Ryosuke,Maeda, Ryohei,Kuwano, Ryoichi
supporting information; experimental part, p. 1639 - 1642 (2012/07/17)
o-(N-Alkylamino)propiophenones are converted into 4-quinolones in the presence of chlorobenzene, potassium phosphate, morpholine, and nickel(0) catalyst. The reaction proceeds through the nickel-catalyzed formation of β-enaminones from o-(N-alkylamino)propiophenones and morpholine, followed by the intramolecular transamination. Georg Thieme Verlag Stuttgart · New York.
