6505-37-9Relevant academic research and scientific papers
CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
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Page/Page column 68-69, (2008/06/13)
The present invention discloses compounds of Formula I: (I) having 11beta -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as the use of the Fomula I and compositions as medicaments to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, Syndrome X, and other conditions associated with hyperglycemia.
Synthesis and evaluation of the anti-mammary tumor activity and of the estrogenic side effects of platinum(II) complexes
Gust, R,Schoenenberger, H
, p. 103 - 115 (2007/10/02)
The synthesis and structural characterization of mammary tumor-inhibiting, diastereomeric platinum(II) complexes with 2,6-Cl2, 2F, 6-Cl, 2-Cl, 6-F and 2,6-F2 substituents (1-PtSO4 to 4-PtSO4) are describ
