6506-21-4Relevant academic research and scientific papers
An expeditious synthesis of dimethyl 1-benzyl-cis-piperidine-3,5-dicarboxylate
Danieli, Bruno,Lesma, Giordano,Passarella, Daniele,Silvani, Alessandra
, p. 69 - 77 (2007/10/03)
A mixture of dimethyl 1-benzyl-cis- and trans-piperidine-3,5-dicarboxylate is prepared in high yields from readily available starting materials, by a reliable procedure. The straightforward conversion of the mixture into the diastereomerically pure cis-isomer, a useful σ-symmetry intermediate for alkaloid synthesis, is also prescribed.
