650609-89-5

Upstream product

• 625386-10-9 2-(4-methoxybenzyl)-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester 
• 2746-25-0 p-Methoxybenzyl bromide 
• 625386-12-1 5-amino-2-(p-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 650609-88-4 2-(4-methoxybenzyl)-5-{2-[2-(2-methoxyethoxy)ethoxy]acetylamino}-2H-pyrazole-3-carboxylic acid methyl ester 

Downstream Products

• 940964-39-6 C₆₆H₈₅N₁₁O₁₅ 
• 940963-92-8 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazolecarbonyl-(S)-alanyl-O⁴-tert-butyl-(S)-aspartyl-amino}-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-91-7 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazole-3-cabonyl-(S)-phenylalanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino}-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-90-6 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazole-3-cabonyl-(S)-alanyl-N⁶-tert-butyloxycarbonyl-(S)-lysyl-amino}-2-(4-methoxybenzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 940963-89-3 5-{5-[2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino]-2-(4-methoxybenzyl)-2H-pyrazol-3-carboxyl-N⁶-tert-butoxycarbonyl-(S)-lysyl-(S)-alanyl-amino}-2-(4-methoxybenzyl)-2H-pyrazol-3-carboxylic acid methyl ester 
• 849599-81-1 C₅₄H₇₈N₁₀O₁₅ 
• 849599-83-3 5-(2-{6-tert-butoxycarbonylamino-2-[(2-(4-methoxy-benzyl)-5-{2-[2-(2-methoxy-ethoxy)-ethoxy]-acetylamino}-2H-pyrazole-3-carbonyl)-amino]-hexanoylamino}-3-methyl-butyrylamino)-2-(4-methoxy-benzyl)-2H-pyrazole-3-carboxylic acid methyl ester 
• 650610-01-8 2-(4-methoxybenzyl)-5-[(2-(4-methoxybenzyl)-5-{2-[2-(2-methoxyethoxy)ethoxy]acetylamino}-2H-pyrazole-3-carbonyl)amino]-2H-pyrazole-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

β-sheet ligands in action: KLVFF recognition by aminopyrazole hybrid receptors in water

Little is known about the precise mechanism of action of β-sheet ligands, hampered by the notorious solubility problems involved with protein misfolding and amyloid formation. Recently the nucleation site for the pathogenic aggregation of the Alzheimer's

Aminopyrazole oligomers for β-sheet stabilization of peptides

A general concept for the stabilization of β-sheets by designed artificial ligands is introduced. The ligands have two key features: they contain acylated 3-aminopyrazoles with a DAD hydrogen bond donor and acceptor pattern, and they were synthesized as o