650636-40-1

Upstream product

• 52805-47-7 1-cyano-2-hydroxynaphthalene 
• 70-11-1 α-bromoacetophenone 
• 7470-09-9 2-hydroxy-1-naphthaldehyde oxime 
• 135-19-3 β-naphthol 

Downstream Products

• 650636-48-9 N-(2-benzoyl-naphtho[2,1-b]furan-1-yl)-acetamide 
• 650636-51-4 N-(2-benzoyl-naphtho[2,1-b]furan-1-yl)-benzamide 
• 847200-32-2 (2-benzoyl-naphtho[2,1-b]furan-1-yl)-carbamic acid ethyl ester 
• 847200-23-1 N-(2-benzoyl-naphtho[2,1-b]furan-1-yl)-2-chloro-acetamide 
• 1133386-84-1 C₂₃H₁₅NO₃ 
• 1133386-85-2 C₂₂H₁₂N₂O₂ 
• 1133386-81-8 C₂₄H₁₇NO₄ 
• 650636-57-0 9-amino-8,10-diphenyl-8,9-dihydro-7-oxa-9,11-diaza-benzo[c]fluoren-8-ol 
• 650636-54-7 9-amino-10-methyl-8-phenyl-8,9-dihydro-7-oxa-9,11-diaza-benzo[c]fluoren-8-ol 
• 847200-39-9 (2-{[(4-nitro-phenyl)-hydrazono]-phenyl-methyl}-naphtho[2,1-b]furan-1-yl)-carbamic acid ethyl ester 
• 847200-38-8 {2-[phenyl-(phenyl-hydrazono)-methyl]-naphtho[2,1-b]furan-1-yl}-carbamic acid ethyl ester 
• 847200-37-7 [2-(hydrazono-phenyl-methyl)-naphtho[2,1-b]furan-1-yl]-carbamic acid ethyl ester 
• 650636-43-4 (1-amino-naphtho[2,1-b]furan-2-yl)-phenyl-methanone oxime 

Relevant academic research and scientific papers

Lewis Acid-Mediated Cyanation of Phenols Using N-Cyano-N-phenyl-p-toluenesulfonamide

Lewis acid-mediated cyanation of phenol derivatives with N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) has been developed. The reaction proceeded efficiently with high regioselectivity to produce aromatic nitriles in moderate to excellent yields, which provides a direct and practical access to valuable products. (Figure presented.).

Synthesis of novel naphtho[2,1-b]furo[3,2-b]pyridine derivatives as potential antimicrobial agents

The starting materials 2-acyl-3-aminonaphtho[2,1-b]furans 4a-b have been directly synthesized from 2-hydroxy-1-naphthaldehyde oxime by treating with a-haloketone through Thrope-Ziegler reaction. The compounds 4a-b undergo Friedlander cyclization on treatment with active methylene compounds, and produce title compounds 5a-b, 6a-b and 7a-b. Some other routes for the synthesis of various derivatives of this new heterocycle have been investigated. All the newly synthesized compounds are characterized by elemental analysis, spectral studies, and have been evaluated for antimicrobial activity.

Synthesis and biological study of some new naphtho[2,1-b]furan and related heterocyclic systems

In the reaction of 1-cyano-2-naphthol (4) or its sodium salt with different alkylating agent, the O-alkylated derivatives (5a-d) were produced which underwent ring closure reactions using sodium ethoxide solution to give aminonaphtho [2,1-b]furan derivati

Synthesis of naphtho[2,1-b]furo[3,2-e]-1,4-diazepin-2-ones and naphtho[2,1-b]furo[3,2-e]-1,3,4-triazepin-2-ones of pharmacological interest

2-Hydroxy-1-naphthonitrile 1 on treatment with different haloketones affords corresponding 2-acyl-3-amino-naphtho[2,1-b]furans 2a-c. The compounds 2a-c on refluxing with chloroacetyl chloride produce 3-chloroacetamido-2- acylnaphtho[2,1-b]furans 3a-c, whi

Synthesis of novel naphtho[2,1-b]furopyrimidine derivatives

2-Acyl-3-aminonaphtho[2,1-b]furans 2a-c are converted into corresponding oximes 3a-c, which on reaction with chloroacetyl chloride in the presence of triethyl amine yield 2-chloromethyl-4-alkyl/arylnaphtho[2,1-b]furo[3,2-d]pyrimidine-3-oxides 4a-c. Acylat