65078-05-9

Basic information

• Product Name: 4-methyl-2-nitrobenzamide
• Synonyms: 4-methyl-2-nitrobenzamide
• CAS NO: 65078-05-9
• Molecular Weight: 180.163
• Mol File: 65078-05-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-methyl-2-nitrobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-nitrobenzamide(65078-05-9)
• EPA Substance Registry System: 4-methyl-2-nitrobenzamide(65078-05-9)

Safety Data

• Hazardous Substances Data: 65078-05-9(Hazardous Substances Data)

Upstream product

• 27329-27-7 4-methyl-2-nitrobenzoic acid 
• 50424-81-2 4-methyl-2-nitro-benzoyl chloride 
• 26830-95-5 4-methyl-2-nitrobenzonitrile 

Downstream Products

• 39549-79-6 2-amino-4-methylbenzamide 
• 923945-96-4 4-methyl-2-nitro-thiobenzamide 
• 75844-40-5 7-methyl-quinazolin-4(3H)-one 
• 1449737-58-9 5-bromo-7-methyl-8-nitro-N-(3-(trifluoromethyl)phenyl)quinazolin-4-amine 
• 943606-89-1 7-methyl-N⁴-(3-(trifluoromethyl)phenyl)quinazoline-4,8-diamine 

Relevant articles and documents

BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.

COMPOUNDS USEFUL FOR INHIBITING CHK1

Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as ther-apeutic agents, for example, in treating cancer and oth