65083-74-1

Basic information

• Product Name: 1-Propanone, 1-(4-hydroxy-3,5-dimethylphenyl)-3-phenyl-
• CAS NO: 65083-74-1
• Molecular Formula: C17H18O2
• Molecular Weight: 254.329
• Mol File: 65083-74-1.mol

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-(4-hydroxy-3,5-dimethylphenyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(4-hydroxy-3,5-dimethylphenyl)-3-phenyl-(65083-74-1)
• EPA Substance Registry System: 1-Propanone, 1-(4-hydroxy-3,5-dimethylphenyl)-3-phenyl-(65083-74-1)

Safety Data

• Hazardous Substances Data: 65083-74-1(Hazardous Substances Data)

Upstream product

• 127311-26-6 2,6-dimethyl-4-(3-phenylpropyl)phenol 
• 576-26-1 2.6-dimethylphenol 
• 645-45-4 hydrocinnamic acid chloride 
• 100-52-7 benzaldehyde 
• 5325-04-2 1-(4-hydroxy-3,5-dimethylphenyl)ethanone 

Relevant articles and documents

Cu(OAc)2-catalyzed remote benzylic C(sp3)-H oxyfunctionalization for C=O formation directed by the hindered para-hydroxyl group with ambient air as the terminal oxidant under ligand- and additive-free conditions

A hindered para-hydroxyl group-directed remote benzylic C(sp3)-H oxyfunctionalization has been developed for the straightforward transformation of 2,6-disubstituted 4-cresols, 4-alkylphenols, 4-hydroxybenzyl alcohols and 4-hydroxybenzyl alkyl ethers into various aromatic carbonyl compounds. The ligand- and additive-free Cu(OAc)2-catalyzed atmospheric oxidation mediated by ethylene glycol unlocks a facile, atom-economical, and environmentally benign C=O formation for the functionalization of primary and secondary benzyl groups. Due to the pharmaceutical importance of 4-hydroxybenzaldehydes and 4-hydroxyphenones, the methodology is expected to be of significant value for both fundamental research and practical applications.

Benzoylethers and processes for their production

Processes for preparing benzoylethers, their acid additive salts and their quaternary ammonium salts are disclosed. These compounds have useful pharmacodynamic properties.