65101-82-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(Morpholin-4-ylmethyl)benzoic acid hydrochloride serves as a key building block in the synthesis of various pharmaceutical compounds due to its chemical properties and solubility in water and polar solvents.
Used in Antiviral Applications:
As a potential antiviral agent, 4-(Morpholin-4-ylmethyl)benzoic acid hydrochloride may be utilized in the development of treatments targeting viral infections, leveraging its chemical structure to interfere with viral replication or assembly.
Used in Anticancer Applications:
4-(Morpholin-4-ylmethyl)benzoic acid hydrochloride holds promise as a potential anticancer agent, possibly contributing to the development of new therapeutic strategies against cancer by targeting specific cellular pathways or mechanisms involved in tumor growth and progression.
Used in Drug Formulation:
The hydrochloride salt form of 4-(Morpholin-4-ylmethyl)benzoic acid enhances its stability, making it suitable for various pharmaceutical formulations, which can improve the compound's bioavailability and therapeutic effectiveness when administered to patients.

InChI:InChI:1S/C12H15NO3.ClH/c14-12(15)11-3-1-10(2-4-11)9-13-5-7-16-8-6-13;/h1-4H,5-9H2,(H,14,15);1H

Upstream product

• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 68453-56-5 methyl 4-(morpholinomethyl)benzoate 

Downstream Products

• 686720-98-9 (4-isopropylpiperazin-1-yl)(4-(morpholinomethyl)phenyl)methanone 
• 934221-39-3 N-(N-(4-morpholinomethylbenzoyl)-L-phenylalanyl)-L-phenylalanol 
• 1338250-31-9 N-(N-(4-morpholinomethylbenzoyl)-L-phenylalanyl)-O-acetyl-L-phenylalanol 
• 123742-32-5 4-(4-Morpholinylmethyl)benzoyl chloride 

Relevant academic research and scientific papers

N-HYDROXYFORMAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THEM FOR USE AS BMP1, TLL1 AND/OR TLL2 INHIBITORS

Compounds of Formulas (I) and (II) and salts thereof; methods of making and using the same, including use for inhibiting BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.

Preparative synthesis of heterocyclic and aromatic N-benzyl amines

A simple and highly efficient procedure has been proposed for the synthesis of heterocyclic and aromatic N-benzyl amines via reductive amination of substituted aromatic aldehydes in the presence of sodium tetrahydridoborate- acetic acid system generating reactive sodium triacetoxyhydridoborate.

Synthesis and biological evaluation of Matijing-Su derivatives as potent anti-HBV agents

A series of Matijing-Su (MTS, N-(N-benzoyl-l-phenylalanyl)-O-acetyl-l- phenylalanol) derivatives were synthesized and evaluated for their anti-hepatitis B virus (HBV) activity in 2.2.15 cells. The IC50 of compounds 14a (0.71 μM), 13c (2.85 μM), 13b (4.37 μM), etc. and the selective index of 13g (161.01), 13c (90.45), 13a (85.09) etc. of the inhibition on the replication of HBV DNA were better than those of the positive control lamivudine (IC50: 82.42 μM, SI: 41.59). Compounds 13o, 13p, and 16a also exhibited significant anti-HBV activity.

PROCESS FOR THE PREPARATION OF PIPERAZINYL AND DIAZEPANYL BENZAMIDE DERIVATIVES

The present invention is directed to a novel process for the preparation of piperazinyl and diazapanyl benzamide derivatives, useful for the treatment of disorders and conditions mediated by a histamine receptor, preferably the H3 receptor.