651045-53-3

Upstream product

• 75-65-0 tert-butyl alcohol 
• 651045-51-1 (1R,2'R)-2,3,4,6-tetra-O-benzylspiro[1,5-anhydro-D-glucitol-1,1'-cyclopropane]-2'-yl isocyanate 
• 651045-48-6 ethyl (1R,2'R)-2,3,4,6-tetra-O-benzylspiro[1,5-anhydro-D-glucitol-1,1'-cyclopropane]-2'-carboxylate 
• 651045-49-7 (1R,2'R)-2,3,4,6-tetra-O-benzylspiro[1,5-anhydro-D-glucitol-1,1'-cyclopropane]-2'-carboxylic acid 
• 133697-34-4 2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-D-gluco-hept-1-enitol 
• 126709-14-6 1-Azi-2,3,4,6-tetra-O-benzyl-1-deoxy-D-glucopyranose 

Downstream Products

• 651045-54-4 tert-butyl-[(1R,2'R)-spiro[1,5-anhydro-D-glucitol-1,1'-cyclopropane]-2'-yl]carbamate 

Relevant academic research and scientific papers

Synthesis of monosaccharide-derived spirocyclic cyclopropylamines and their evaluation as glycosidase inhibitors

The glucose-, mannose-, and galactose-derived spirocyclic cyclopropylammonium chlorides 1a - 1d, 2a - 2d and 3a-3d were prepared as potential glycosidase inhibitors. Cyclopropanation of the diazirine 5 with ethyl acrylate led in 71% yield to a 4:5:1:20 mi