651045-79-3Relevant academic research and scientific papers
Synthesis of monosaccharide-derived spirocyclic cyclopropylamines and their evaluation as glycosidase inhibitors
Bluechel, Christian,Ramana, Chepuri Venkata,Vasella, Andrea
, p. 2998 - 3036 (2007/10/03)
The glucose-, mannose-, and galactose-derived spirocyclic cyclopropylammonium chlorides 1a - 1d, 2a - 2d and 3a-3d were prepared as potential glycosidase inhibitors. Cyclopropanation of the diazirine 5 with ethyl acrylate led in 71% yield to a 4:5:1:20 mi
