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2,6-anhydro-3,4,5,7-tetra-O-benzyl-1-deoxy-β-D-manno-hept-1-enitol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

97321-70-5

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97321-70-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 97321-70-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,3,2 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 97321-70:
(7*9)+(6*7)+(5*3)+(4*2)+(3*1)+(2*7)+(1*0)=145
145 % 10 = 5
So 97321-70-5 is a valid CAS Registry Number.

97321-70-5Relevant articles and documents

Stereoselective Palladium-Catalyzed Arylation of Exo-Glycals with Aryl Iodides

Regier, Jeffery,Ghanty, Supriya,Bolshan, Yuri

supporting information, p. 524 - 530 (2022/01/12)

A novel methodology for the arylation of exo-glycals has been developed. A range of exo-glycals underwent reactions with aryl iodides in the presence of a palladium catalyst. The transformation proceeded in a stereoselective manner to afford Z-isomers. Th

Highly stereoselective synthesis of aryl/heteroaryl-: C -nucleosides via the merger of photoredox and nickel catalysis

Ma, Yingying,Liu, Shihui,Xi, Yifan,Li, Hongrui,Yang, Kai,Cheng, Zhihao,Wang, Wei,Zhang, Yongqiang

, p. 14657 - 14660 (2019/12/11)

A photoredox/nickel dual-catalyzed decarboxylative cross-coupling reaction of anomeric ribosyl/deoxyribosyl acids with aryl/heteroaryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the using of cost-effective and easily handled catalysts and starting materials, which allows the highly stereoselective synthesis of diverse aryl/heteroaryl-C-nucleosides in moderate to high yields.

Stereoselective Synthesis of C, C-Glycosides from exo-Glycals Enabled by Iron-Mediated Hydrogen Atom Transfer

Tardieu, Damien,Desnoyers, Marine,Laye, Claire,Hazelard, Damien,Kern, Nicolas,Compain, Philippe

supporting information, p. 7262 - 7267 (2019/10/11)

We describe herein a convenient strategy for the construction of C,C-glycoside building blocks via the intermediacy of tertiary pseudoanomeric radicals. Application of an iron-mediated hydrogen atom transfer/Michael-Giese coupling enables the anomeric quaternization of readily available exo-glycals with good to complete stereocontrol in the pyranose and furanose series. Carefully optimized conditions allow the use of challenging trisubstituted derivatives prone to undergo further elaboration to stable neoglycoconjugates. Preliminary results for direct C-disaccharide synthesis are also discussed.

Highly (Z)-Diastereoselective Synthesis of Trifluoromethylated exo-Glycals via Photoredox and Copper Catalysis

Frédéric, Christophe J.-M.,Cornil, Jér?me,Vandamme, Mathilde,Dumitrescu, Lidia,Tikad, Abdellatif,Robiette, Rapha?l,Vincent, Stéphane P.

supporting information, p. 6769 - 6773 (2018/10/24)

Highly (Z)-diastereoselective approaches for the synthesis of trifluoromethylated exo-glycals by copper and photoredox catalysis are described. These complementary reactions are applicable to a wide range of methylene exo-glycals generated from the corresponding pyranoses and furanoses and give trifluoromethylated compounds under mild conditions in moderate to good yields. DFT calculations have allowed a rationalization of the observed (Z)-stereoselectivity.

Improved synthesis of the C-glucuronide/glycoside of 4-hydroxybenzylretinone (4-HBR)

Cavanaugh, Kathryn R.,Narayanasamy, Sureshbabu,Walker, Joel R.,Clagett-Dame, Margaret,Curley, Robert W.

, p. 249 - 260 (2016/10/22)

Improvements in the synthesis of carbon-linked glucuronide/ glucoside conjugates of cancer chemopreventive retinoids have been achieved starting with 2,3,4,6-tetra-Obenzyl- D-glucopyranose. The revised approach demonstrates better yields, eliminates the use of an expensive, carcinogenic protecting group reagent, and avoids much painstaking chromatography. The new approach should allow synthesis of larger quantities of the agents for detailed animal and mechanistic studies.

Heck-type cross-coupling between halo-exo-glycals and endo-glycals: A practical way to achieve C-glycosidic disaccharides

Tao, Yongfeng,Ding, Ning,Ren, Sumei,Li, Yingxia

, p. 6101 - 6104 (2013/10/22)

An effective Heck-type cross-coupling reaction between halo-exo-glycals and endo-glycals to achieve C-glycosidic disaccharides has been developed. Using Pd(OAc)2 as the catalyst, dppp as ligand and K2CO 3 as base, the reac

Synthesis of N-aryl spiro-sulfamides as potential glycogen phosphorylase inhibitors

Tite, Tony,Tomas, Loic,Docsa, Tibor,Gergely, Pal,Kovensky, José,Gueyrard, David,Wadouachi, Anne

supporting information; experimental part, p. 959 - 961 (2012/03/26)

A new C-glucosylated spiro-sulfamide has been prepared and evaluated toward glycogen phosphorylase inhibition. The synthesis was carried out successfully by nucleophilic displacement of 1-O-tosyl or 1-deoxy-1-iodo-α-d-gluco- hept-2-ulopyranose tetra-O-benzylated derivative using aryl amines, followed by the formation of the corresponding cyclic sulfamide.

Highly efficient synthesis of ketoheptoses

Waschke, Daniel,Thimm, Julian,Thiem, Joachim

, p. 3628 - 3631 (2011/09/15)

A reliable, facile, high overall yielding and diastereoselective synthesis of ketoheptoses was developed and applied for preparation of the two most diabetogenic ketoheptoses as well as in a modified version for the synthesis of kamusol.

A one-pot procedure for methylenating carbonyl compounds using the Nysted reagent and titanocene dichloride

Haahr, Adam,Rankovic, Zoran,Hartley, Richard C.

scheme or table, p. 3020 - 3022 (2011/06/23)

The combination of the Nysted reagent and titanocene dichloride methylenates aldehydes and ketones to give alkenes, and in a microwave-assisted process, esters and lactones give enol ethers. The methylenating agent in this one-pot procedure is presumed to be titanocene methylidene, which is the same reactive intermediate as that generated from Tebbe, Petasis and Grubbs reagents, each of which have to be prepared before use.

DETECTION OF MYCOBACTERIA

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Page/Page column 38, (2011/04/18)

A method for determining the presence of mycobacteria species in an organism or biological sample, the method comprising adding to the organism or biological sample a probe molecule comprising a substrate and a label, which probe molecule can be incorporated into mycobacteria, the presence of mycobacteria being determined by a detector responsive to the presence of the label, optionally after applying a stimulus; suitable probe molecules include compounds comprising a label and a substrate, which label is can be detected by a detector responsive to the presence of the label, optionally after applying a stimulus, characterised by compound being able to engage with the active site of Antigen 85B (Ag85B) such that it can form simultaneous hydrogen bonds with two or more amino acids in the active site selected from Arg 43, Trp 264, Ser126, His 262 and Leu 42, or the corresponding amino acids in Antigen 85A (Ag85A) or Antigen 85C (Ag85C), at least one of which is with Ser126.

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