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1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester, also known as 4-(2-methylphenyl)pyridine-1-carboxylic acid phenyl ester, is a chemical compound that serves as a crucial building block in the pharmaceutical industry. It is a white crystalline solid with a molecular formula of C21H17NO2 and a molecular weight of 315.36 g/mol. 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester is known for its applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate for the production of antiviral and antifungal medications. Due to its potential health and environmental hazards, it is essential to handle 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester with care.

651053-67-7

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651053-67-7 Usage

Uses

Used in Pharmaceutical Industry:
1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for [application reason]. Its role in the development of antiviral and antifungal medications makes it a valuable component in the fight against infectious diseases.
Used in Agrochemical Industry:
In the agrochemical industry, 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester is used as a building block for the creation of various agrochemicals that help protect crops and enhance agricultural productivity. Its versatility in chemical synthesis allows for the development of effective solutions against pests and diseases in the agricultural sector.

Check Digit Verification of cas no

The CAS Registry Mumber 651053-67-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,1,0,5 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 651053-67:
(8*6)+(7*5)+(6*1)+(5*0)+(4*5)+(3*3)+(2*6)+(1*7)=137
137 % 10 = 7
So 651053-67-7 is a valid CAS Registry Number.

651053-67-7Relevant academic research and scientific papers

Efficient Solution-Phase Parallel Synthesis of 4-Substituted N-Protected Piperidines

Wang, Xiaoyang,Kauppi, Anna M.,Olsson, Roger,Almqvist, Fredrik

, p. 4586 - 4592 (2003)

Practical conditions for the synthesis of 4-substituted N-protected piperidines through CuCN·2LiBr-catalyzed organozinc additions to 1-acylpyridinium salts and subsequent hydrogen-transfer hydrogenation have been established. The reaction sequence is performed at room temperature and provides 4-substituted N-protected piperidines in excellent overall yields without the isolation of intermediate dihydropyridines, In those cases in which the organozinc addition results in mixtures of 2- and 4-substituted dihydropyridines, the 2-substituted isomers are efficiently scavenged with maleic anhydride and subsequently removed by a mild extractive workup with NaHCO3 (sat.). The N-acyl group can conveniently be exchanged from N-phenoxycarbonyl to N-tBoc, thus allowing orthogonal deprotection strategies. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

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