1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester

Base Information

Chemical Name:1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester
CAS No.:651053-67-7
Molecular Formula:C19H17NO2
Molecular Weight:291.349
Hs Code.:
DSSTox Substance ID:DTXSID00465913

Synonyms:651053-67-7;1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester;DTXSID00465913

Suppliers and Price of 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:291.125928785
Heavy Atom Count:22
Complexity:423

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1C2C=CN(C=C2)C(=O)OC3=CC=CC=C3

Technology Process of 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester

There total 1 articles about 1(4H)-Pyridinecarboxylic acid, 4-(2-methylphenyl)-, phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 110-86-1
pyridine

: 1885-14-9
phenyl chloroformate

: 2-methylphenylzinc bromide

: 651053-67-7
4-o-tolyl-4H-pyridine-1-carboxylic acid phenyl ester

Guidance literature:: pyridine; phenyl chloroformate; CuCN*2LiBr; In tetrahydrofuran; at 20 ℃;

2-methylphenylzinc bromide; In tetrahydrofuran; at 20 ℃; for 1h; Further stages.;
DOI:10.1002/ejoc.200300387

Reference yield: 92.0%

: 651053-67-7
4-o-tolyl-4H-pyridine-1-carboxylic acid phenyl ester

: 651053-87-1
phenyl 4-(2'-methylphenyl)piperidine-1-carboxylate

Guidance literature:: With ammonium formate; palladium on activated charcoal; In tetrahydrofuran; methanol; at 20 ℃;
DOI:10.1002/ejoc.200300387

Reference yield:

: 651053-67-7
4-o-tolyl-4H-pyridine-1-carboxylic acid phenyl ester

: 630116-52-8
4-(2'-methylphenyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / ammonium formate / Pd/C / tetrahydrofuran; methanol / 20 °C

2: 80 percent / KOH; NH₂NH₂*H₂O / ethane-1,2-diol / 1 h / Heating

With potassium hydroxide; ammonium formate; hydrazine hydrate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethylene glycol;
DOI:10.1002/ejoc.200300387