65112-28-9Relevant academic research and scientific papers
Synthesis, spectroscopic and biological properties of bis(3- arylimidazolidinyl-1)methanes. A novel family of antimicrobial agents
Perillo, Isabel,Repetto, Evangelina,Caterina, Maria Cristina,Massa, Rosana,Gutkind, Gabriel,Salerno, Alejandra
, p. 811 - 815 (2005)
Synthesis, spectroscopic and biological properties of new bis(3-arylimidazolidinyl-1)methanes are described. These compounds were synthesized by condensation reaction between N-arylethylenediamines and formaldehyde. Chemical structures were confirmed by means of their 1H- and 13C-NMR and mass spectroscopic data. Investigation of in vitro antimicrobial activity was performed using Gram-negative and Gram-positive bacteria as well as antifungal studies against Aspergillus niger and Candida albicans. Minimal inhibitory concentrations of active compounds were determined.
