65114-77-4

Basic information

• Product Name: Thymidine, 3'-(2-chlorophenyl phenylphosphoramidate), (S)-
• CAS NO: 65114-77-4
• Molecular Formula: C22H23ClN3O7P
• Molecular Weight: 507.867
• Mol File: 65114-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thymidine, 3'-(2-chlorophenyl phenylphosphoramidate), (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 3'-(2-chlorophenyl phenylphosphoramidate), (S)-(65114-77-4)
• EPA Substance Registry System: Thymidine, 3'-(2-chlorophenyl phenylphosphoramidate), (S)-(65114-77-4)

Safety Data

• Hazardous Substances Data: 65114-77-4(Hazardous Substances Data)

Upstream product

• 42926-80-7 5'-O-(4-monomethoxytrityl)-2'-deoxythymidine 
• 69320-80-5 o-chlorophenyl N-phenylphosphoramido chloridate 
• 61941-23-9 5'-O-monomethoxytritylthymidine 3'-O-(2-chlorophenyl) phosphoranilidate 

Downstream Products

• 76746-49-1 thymidine cyclic 3'-5'-phosphoranilidate 

Relevant articles and documents

2'-DEOXYRIBONUCLEOSIDE 3'-ARYL PHOSPHORANILIDATES KEY INTERMEDIATES IN THE STEREOSPECIFIC SYNTHESIS OF 2'-DEOXYRIBONUCLEOSIDE CYCLIC 3',5'-PHOSPHOROTHIOATES AND DINUCLEOSIDE(3'->5')-PHOSPHOROTHIOATES

Phosphorylation of the 5'-O-monomethoxytrityl-2'-deoxyribonucleosides by means of aryl phosphoranilidochloridates gives the diastereomers of 5'-O-monomethoxytrityl-2'-deoxyribonucleoside 3'-aryl phosphoranilidates.Their separation can be performed by mean