6512-57-8

Basic information

• Product Name: diethyl 1-phenylnaphthalene-2,3-dicarboxylate
• CAS NO: 6512-57-8
• Molecular Formula: C₂₂H₂₀O₄
• Molecular Weight: 348.3918
• Mol File: 6512-57-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 483°C at 760 mmHg
• Flash Point: 241.4°C
• Density: 1.17g/cm³
• Vapor Pressure: 1.74E-09mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: diethyl 1-phenylnaphthalene-2,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 1-phenylnaphthalene-2,3-dicarboxylate(6512-57-8)
• EPA Substance Registry System: diethyl 1-phenylnaphthalene-2,3-dicarboxylate(6512-57-8)

Safety Data

• Hazardous Substances Data: 6512-57-8(Hazardous Substances Data)

Upstream product

• 2216-94-6 phenylpropynoic acid ethyl ester 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 141-05-9 Diethyl maleate 
• 31378-03-7 1-phenyl-2-tosylethanone 
• 100-52-7 benzaldehyde 
• 99-87-6 4-methylisopropylbenzene 

Relevant articles and documents

APEX Strategy Represented by Diels–Alder Cycloadditions—New Opportunities for the Syntheses of Functionalised PAHs

Diels–Alder cycloaddition of various dienophiles to the bay region of polycyclic aromatic hydrocarbons (PAHs) is a particularly effective and useful tool for the modification of the structure of PAHs and thereby their final properties. The Diels–Alder cycloaddition belongs to the single-step annulative π-extension (APEX) reactions and represents the maximum in synthetic efficiency for the constructions of π-extended PAHs including functionalised ones, nanographenes, and π-extended fused heteroarenes. Herein we report new applications of the APEX strategy for the synthesis of derivatives of 1,2-diarylbenzo[ghi]perylene, 1,2-diarylbenzo[ghi]perylenebisimide and 1,2-disubstituted-benzo[j]coronene. Namely, the so far unknown cycloaddition of 1,2-diarylacetylenes into the perylene and perylenebisimide bay regions was used. 1,2-Disubstituted-benzo[j]coronenes were obtained via cycloaddition of benzyne into 1,2-diarylbenzo[ghi]perylenes by using a new highly effective system for benzyne generation and/or high pressure conditions. Moreover, we report an unprecedented Diels–Alder cycloaddition–cycloaromatisation domino-type reaction between 1,4-(9,9-dialkylfluoren-3-yl)-1,3-butadiynes and perylene. The obtained diaryl-substituted core-extended PAHs were characterised by DFT calculation as well as electrochemical and spectroscopic measurements.

A novel multicomponent reaction of arynes, β-keto sulfones, and Michael-type acceptors: A direct synthesis of polysubstituted naphthols and naphthalenes

(Chemical Equation Presented) A novel multicomponent reaction of arynes, β-keto sulfones, and Michael-type acceptors is presented, providing an efficient method for the synthesis of polysubstituted naphthols and polysubstituted naphthalenes. Further investigation suggests that the tandem reaction may proceed via a sequential nucleophilic attack to arynes, intramolecular nucleophilic substitution followed by a Michael addition, and a ring closure - elimination process.