6512-67-0

Basic information

• Product Name: (3S,4S)-3-(4-hydroxy-3,5-dimethoxybenzyl)-4-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
• Synonyms: 2(3H)-Furanone, dihydro-3-((4-hydroxy-3,5-dimethoxyphenyl)methyl)-4-((4-hydroxy-3-methoxyphenyl)methyl)-, (3S-trans)-
• CAS NO: 6512-67-0
• Molecular Formula: C₂₁H₂₄O₇
• Molecular Weight: 388.4111
• Mol File: 6512-67-0.mol

Chemical Properties

• Boiling Point: 614.4°C at 760 mmHg
• Flash Point: 216.2°C
• Density: 1.287g/cm³
• Vapor Pressure: 1.09E-15mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: (3S,4S)-3-(4-hydroxy-3,5-dimethoxybenzyl)-4-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-3-(4-hydroxy-3,5-dimethoxybenzyl)-4-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one(6512-67-0)
• EPA Substance Registry System: (3S,4S)-3-(4-hydroxy-3,5-dimethoxybenzyl)-4-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one(6512-67-0)

Safety Data

• Hazardous Substances Data: 6512-67-0(Hazardous Substances Data)

Upstream product

• 84755-39-5 acide (benzyloxy-4 methoxy-3 phenyl)-4 methoxycarbonyl-3 butene-3 oique 
• 92831-74-8 4-<<4-(benzyloxy)-3-methoxyphenyl>methyl>dihydro-2(3H)-furanone 
• 121-33-5 vanillin 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 927198-76-3 (+/-)-2-(4-benzyloxy-3-methoxybenzyl)butanedioic acid 1-methyl ester 
• 134-96-3 syringic aldehyde 
• 84755-40-8 (hydroxy-4 methoxy-3 benzyl)-4 dihydro-3H-furannone-2 
• 140193-23-3 (+/-)-3-<(4-Tertio-butyl dimethylsiloxy)-3-methoxybenzyl>butan-4-olide 
• 111194-05-9 2-(benzyloxy)-5-(bromomethyl)-1,3-dimethoxybenzene 
• 6527-32-8 4-(benzyloxy)-3,5-dimethoxybenzaldehyde 
• 2176-18-3 4-benzyloxy-3,5-dimethoxybenzyl alcohol 
• 111265-99-7 C₁₃H₁₄O₆^(2-)*2K⁽¹⁺⁾ 
• 111266-00-3 (R)-4-<(4-hydroxy-3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 111266-03-6 (R)-(+)-3-(4-benzyloxy-3-methoxybenzyl)-γ-butyrolactone 

Relevant articles and documents

Oxidative cyclization reaction of dibenzylbutanolides with combined utilization of synthetic chemistry and biotechnological methods

We reported plant cell culture (as an enzyme source)-catalyzed oxidative cyclization reaction of dibenzylbutanolides (1a, b, d, e) to cyclic product (2a, b, d, e) via a hypothetical quinone methide intermediate.

Biosynthesis of yatein in Anthriscus sylvestris.

Little is known about the biosynthesis of yatein, in spite of its importance as a typical heartwood lignan and a key biosynthetic intermediate of the antitumor lignan podophyllotoxin. The present study, based on individual administration of [13C]phenylalanine and deuterium labelled lignans and simultaneous administration of two distinct lignans labelled with deuterium atoms to Anthriscus sylvestris, established the two independent branch pathways from matairesinol, one to afford yatein via thujaplicatin, 5-methylthujaplicatin, and 4,5-dimethylthujaplicatin and the other to bursehernin via pluviatolide. The latter pathway did not lead to yatein, eliminating the presence of a metabolic grid from matairesinol to yatein.

THE SYNTHESES OF (R)-(+)-β-VANILLYL-γ-BUTYROLACTONE AND OF CHIRAL LIGNANS THEREFROM

(R)-(+)-β-vanillyl-γ-butyrolactone was obtained in 4 steps including a resolution, from vanillin and dimethyl succinate, and was used for the total syntheses of 5 naturally occurring and optically active lignans such as (+)-isolariciresinol 20.