651322-82-6

Upstream product

• 151417-98-0 2-(2-hydroxymethyl-3,6-dimethoxyphenyl)-1,3-dithiolane 
• 651322-89-3 2-(2-benzyloxymethyl-3,6-dimethoxy-phenyl)-[1,3]dithiolane 

Downstream Products

• 651322-83-7 3-(2-benzyloxymethyl-3,6-dioxo-cyclohexa-1,4-dienyl)-3-hydroxy-propionic acid tert-butyl ester 
• 649774-55-0 3-(8-benzyloxymethyl-11-hydroxy-2-methyl-4-octyloxymethoxy-3,7,10-trioxo-2,3,7,10-tetrahydro-1H-naphtho[2,3-e]isoindol-9-yl)-3-hydroxy-propionic acid tert-butyl ester 

Relevant academic research and scientific papers

Studies Directed toward the Total Synthesis of Lactonamycin: Control of the Sense of Cycloaddition of a Quinone through Directed Intramolecular Catalysis

The rapid assembly of the ABCD tetracyclic ring system of lactonamycin involved the strong-base-induced regioselective Diels-Alder reaction of 1 and 2 to form advanced precursor 3. Regiochemical control results from the suitably positioned hydroxy group,