651335-56-7 Usage
Chemical Structure
1H-Indole, 1-[1-(phenylmethyl)-4-piperidinyl]-3-(phenylsulfonyl)is a complex compound with an indole ring, a piperidine ring, and a phenylsulfonyl group.
Indole Ring
A five-membered aromatic ring with a nitrogen atom at one position and a carbonyl group at the opposite position.
Piperidine Ring
A six-membered nitrogen-containing ring, attached to the indole ring, contributing to the compound's structure and properties.
Phenylmethyl Group
A benzene ring attached to a methyl group, connected to the indole ring through the piperidinyl group.
Phenylsulfonyl Group
A benzene ring attached to a sulfonyl group (-SO2), connected to the third position of the indole ring.
Pharmacological Properties
The compound may exhibit biological activity and could be used in pharmaceutical research for drug development targeting specific pathways.
Potential Applications
1H-Indole, 1-[1-(phenylmethyl)-4-piperidinyl]-3-(phenylsulfonyl)could be used in the development of new drugs for various therapeutic areas, depending on its pharmacological properties and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 651335-56-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,1,3,3 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 651335-56:
(8*6)+(7*5)+(6*1)+(5*3)+(4*3)+(3*5)+(2*5)+(1*6)=147
147 % 10 = 7
So 651335-56-7 is a valid CAS Registry Number.
651335-56-7Relevant academic research and scientific papers
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT6 receptor modulators
Bernotas, Ronald C.,Antane, Schuyler,Shenoy, Rajesh,Le, Van-Duc,Chen, Ping,Harrison, Boyd L.,Robichaud, Albert J.,Zhang, Guo Ming,Smith, Deborah,Schechter, Lee E.
scheme or table, p. 1657 - 1660 (2010/07/03)
Novel 3-(arylsulfonyl)-1-(azacyclyl)-1H-indoles 6 were synthesized as potential 5-HT6 receptor ligands, based on constraining a basic side chain as either a piperidine or a pyrrolidine. Many of these compounds had good 5-HT6 binding affinity with Ki values 50 = 60 nM, Emax = 70%) and antagonists (6y: IC50 = 17 nM, Imax = 86%) were identified in a 5-HT6 adenylyl cyclase assay.
