651335-70-5 Usage
Chemical structure
1H-Indole, 1-(1-ethyl-3-piperidinyl)-3-(phenylsulfonyl)is composed of an indole ring with a piperidine group attached at the 1-position and a phenylsulfonyl group at the 3-position.
Pharmacological activity
The presence of the piperidine group suggests that 1H-Indole, 1-(1-ethyl-3-piperidinyl)-3-(phenylsulfonyl)- may have pharmacological activity, potentially affecting the central nervous system.
Protecting group
The phenylsulfonyl group is often used as a protecting group in organic synthesis, which may be relevant for the compound's potential applications in chemical production.
Potential applications
1H-Indole, 1-(1-ethyl-3-piperidinyl)-3-(phenylsulfonyl)may have potential applications in medicinal chemistry or as a synthetic intermediate.
Further research needed
More research is required to fully understand the properties and potential uses of 1H-Indole, 1-(1-ethyl-3-piperidinyl)-3-(phenylsulfonyl)-.
Check Digit Verification of cas no
The CAS Registry Mumber 651335-70-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,1,3,3 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 651335-70:
(8*6)+(7*5)+(6*1)+(5*3)+(4*3)+(3*5)+(2*7)+(1*0)=145
145 % 10 = 5
So 651335-70-5 is a valid CAS Registry Number.
651335-70-5Relevant academic research and scientific papers
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT6 receptor modulators
Bernotas, Ronald C.,Antane, Schuyler,Shenoy, Rajesh,Le, Van-Duc,Chen, Ping,Harrison, Boyd L.,Robichaud, Albert J.,Zhang, Guo Ming,Smith, Deborah,Schechter, Lee E.
scheme or table, p. 1657 - 1660 (2010/07/03)
Novel 3-(arylsulfonyl)-1-(azacyclyl)-1H-indoles 6 were synthesized as potential 5-HT6 receptor ligands, based on constraining a basic side chain as either a piperidine or a pyrrolidine. Many of these compounds had good 5-HT6 binding affinity with Ki values 50 = 60 nM, Emax = 70%) and antagonists (6y: IC50 = 17 nM, Imax = 86%) were identified in a 5-HT6 adenylyl cyclase assay.
