651335-52-3 Usage
Chemical Family
Indole family
The compound belongs to the indole family of heterocyclic compounds.
Bicyclic Structure
Derivative of 1H-indole
It is a derivative of 1H-indole, which is a bicyclic heterocyclic compound.
Sulfonamide Group
Attached to the phenyl ring
The compound has a sulfonamide group attached to the phenyl ring, which imparts specific chemical and biological properties.
Piperidine Group
Attached to the indole ring
A piperidine group is attached to the indole ring, further contributing to the compound's unique properties.
Potential Applications
Pharmaceuticals, agrochemicals, and materials science
The compound's structure and properties make it useful in various applications, such as pharmaceuticals, agrochemicals, and materials science.
Synthesis Building Block
Complex molecule synthesis
The compound's structure and reactivity make it a valuable building block for the synthesis of other complex molecules.
Pharmacological Properties
Potential drug development
The compound's pharmacological properties could make it a potential candidate for the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 651335-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,1,3,3 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 651335-52:
(8*6)+(7*5)+(6*1)+(5*3)+(4*3)+(3*5)+(2*5)+(1*2)=143
143 % 10 = 3
So 651335-52-3 is a valid CAS Registry Number.
651335-52-3Relevant academic research and scientific papers
3-(Arylsulfonyl)-1-(azacyclyl)-1H-indoles are 5-HT6 receptor modulators
Bernotas, Ronald C.,Antane, Schuyler,Shenoy, Rajesh,Le, Van-Duc,Chen, Ping,Harrison, Boyd L.,Robichaud, Albert J.,Zhang, Guo Ming,Smith, Deborah,Schechter, Lee E.
scheme or table, p. 1657 - 1660 (2010/07/03)
Novel 3-(arylsulfonyl)-1-(azacyclyl)-1H-indoles 6 were synthesized as potential 5-HT6 receptor ligands, based on constraining a basic side chain as either a piperidine or a pyrrolidine. Many of these compounds had good 5-HT6 binding affinity with Ki values 50 = 60 nM, Emax = 70%) and antagonists (6y: IC50 = 17 nM, Imax = 86%) were identified in a 5-HT6 adenylyl cyclase assay.
