651355-76-9

Upstream product

• 651356-55-7 (3R,4R,5R,6S,7S)-7-(tert-Butyl-dimethyl-silanyloxy)-4,6-bis-(tert-butyl-dimethyl-silanyloxymethyl)-3,5-dihydroxy-7-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-heptanoic acid methoxy-methyl-amide 
• 651355-70-3 (R)-3-((2R,3S,4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-5-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-2-vinyl-pentanoyl)-4-isopropyl-oxazolidin-2-one 
• 651355-72-5 (1S,2S,3R,4S)-1-(tert-Butyl-dimethyl-silanyloxy)-2,4-bis-(tert-butyl-dimethyl-silanyloxymethyl)-1-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-hex-5-en-3-ol 
• 651355-73-6 (2S,3S,4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-2,4-bis-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-5-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-pentanal 
• 651355-71-4 (2S,3R,4S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-2-vinyl-pentane-1,3-diol 
• 651355-67-8 (2S,3R)-2-[(1S,2R)-1-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-but-3-enyl]-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxirane 
• 651355-69-0 (2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-propionaldehyde 
• 236117-59-2 (R)-2-((S)-(tert-Butyl-dimethyl-silanyloxy)-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-methyl)-but-3-en-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 651355-74-7 (3S,4R,5R,6S,7S)-7-(tert-Butyl-dimethyl-silanyloxy)-4,6-bis-(tert-butyl-dimethyl-silanyloxymethyl)-3,5-dihydroxy-7-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-heptanoic acid methoxy-methyl-amide 

Downstream Products

• 651355-78-1 (3S,4R,6R,7S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-4,6-bis-(tert-butyl-dimethyl-silanyloxymethyl)-7-{(2S,3R)-3-[(S)-2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-oxiranyl}-5-oxo-heptanoic acid methoxy-methyl-amide 

Relevant academic research and scientific papers

Total synthesis of natural myriaporones

The relative and absolute configuration of the cytotoxic myriaporones. (e.g. 4) was assigned by their total synthesis from aldehyde 1. Key steps included aldol reactions with chiral oxazolidinone 2 and with Weinreb amide 3. TBS = tert-butyldimethylsilyl,