65136-45-0Relevant academic research and scientific papers
A novel C-C bond formation reaction with 1-methoxymethylindolylborate
Ishikura, Minoru,Kato, Hiromi,Ohnuki, Nobuyuki
, p. 220 - 221 (2007/10/03)
The reaction of 1-methoxymethylindolylborates 2 with electrophiles in the presence of benzaldehyde enabled the novel construction of tri-substituted indoles in a 'one-pot' procedure.
Functionalization of the Methyl Group of 2-Methylindole by Direct Generation of a C,N-Dianion
Inagaki, Satoshi,Nishizawa, Yoshihiro,Sugiura, Takashi,Ishihara, Hideharu
, p. 179 - 180 (2007/10/02)
The first method for directly generating C,N-dianion from an alkyl-substituted ?-excessive N-heterocyclic compound (2-methylindole) has been developed.It involves treatment with 3 equiv. of BuLi and 2 equiv. of ButOK in a particular sequence and results in the functionalization of the 2-methyl group of the indole in a regiospecific manner.
VINYLOXYBORANE PROMOTED 1,4-ADDITION OF TRIETHYL(1-METHYLINDOL-2-YL)BORATE TO 2-CYCLOALKENONES
Ishikura, Minoru,Terashima, Masanao
, p. 2091 - 2094 (2007/10/02)
The conjugate addition reaction of triethyl(1-methylindol-2-yl)borate to 2-cycloalkenone could be effected with a catalytic amount of vinyloxyborane.
Novel Aspects on the Reaction of Trialkyl-(1-methylindol-2-yl)borates
Ishikura, Minoru,Terashima, Masanao
, p. 135 - 136 (2007/10/02)
A new use of trialkyl-(1-methylindol-2-yl)borates for the synthesis of 2-substituted indoles involving the palladium catalysed cross-coupling with vinylic and aromatic halides, or a facile alkyl migration from boron to carbon without an additional electrophile is described.
