6515-24-8

Upstream product

• 57601-14-6 2'-hydroxy-3,4,4'-trimethoxychalcone 
• 139006-37-4 cis-3-hydroxy-3',4',7-trimethoxyflavanone dimethylacetal 
• 186581-53-3 diazomethane 
• 77-78-1 dimethyl sulfate 
• 4382-36-9 (+/-)-2,3-trans-fustin 

Downstream Products

• 13798-88-4 (+/-)-fustin 3-acetyl-7,3',4'-trimethyl ether 
• 1166-04-7 (+/-)-gleditsin 7,3',4'-trimethyl ether 
• 96582-13-7 (+/-)-3t,4t-Bis-benzoyloxy-2r-(3,4-dimethoxy-phenyl)-7-methoxy-chroman 
• 1166-04-7 (+/-)-mollisacacidin 7,3',4'-trimethyl ether 
• 62849-14-3 2-Hydroxy-6-methoxy-2-<3,4-dimethoxy-benzyl>-cumaran-3-on 

Relevant academic research and scientific papers

Hypervalent iodine oxidation of 2'-hydroxychalcones: Synthesis of cis-3-hydroxyflavanones

Oxidation of 2'-hydroxychalcones (1a-h) using C6H5I(OAC)2-KOH/MeOH leads to the formation of cis-3-hydroxyflavanone dimethylacetals (2a-h).Mild acid hydrolysis (50percent AcOH) of 2a-h affords cis-3-hydroxyflavanones (3a-h) in good yields.Oxidation of cha

HETEROCYCLES. XVIII. SYNTHESIS OF THE RACEMATES OF NATURALLY OCCURRING FLAVONOIDS

Racemic aromadendrin and fustin have been stereoselectively synthesized.Reduction of the O-substituted derivatives of these flavanonols provides the corresponding derivatives of gleditsin, leucopelargonidin and mollisacacidin (leucofisetinidin).

Metabolites from the Purple Heartwood of Mimosoideae. Part 3. Acacia crombei C.T. White: Structure and Partial Synthesis of Crombenin, A Natural Spiropeltogynoid

Crombenin, 4,4',6,6',7-pentahydroxyisochroman-3'-spirobenzofuran-3(2H)-one, the first spiropeltogynoid, is related to the concominant crombeone (8-hydroxypeltogynone) from which it is derived via oxidation with alkaline hydrogen peroxide of the chalcone i

Flavonoid synthesis based on photolysis of flavan-3-ols, 3-hydroxyflavanones, and 2-benzylbenzofuranones

Irradiation of flavan-3-ols, 3-hydroxyflavanones, and 2-benzylbenzofuranones in methanol leads mainly to photochemical opening of the heterocyclic ring, or to its complete photofragmentation, the products being trapped by reaction with the solvent. Fission of exocyclic C-O bonds also occurs, accompanied by intramolecular rearrangements. The course of these reactions is often dependent on the position and nature of substituents. The conversions provide novel routes to 1,3-diaryl-1-methoxypropan-2-ols, 1,3-diaryl-2,2-dimethoxypropan-1-ones, cis-3-methoxyflavanones, isoflavones, flavanones, and trans-chalcones, and hence to α-hydroxychalcones, cis- and trans-α-methoxychalcones, and 2-methoxy-2-(α-methoxybenzyl)benzofuranones.