651780-07-3

Basic information

• Product Name: ethyl 3-(4-bromo-2-hydroxyphenyl)-3-oxopropanoate
• Synonyms: ethyl 3-(4-bromo-2-hydroxyphenyl)-3-oxopropanoate
• CAS NO: 651780-07-3
• Molecular Weight: 287.11
• Mol File: 651780-07-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 3-(4-bromo-2-hydroxyphenyl)-3-oxopropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(4-bromo-2-hydroxyphenyl)-3-oxopropanoate(651780-07-3)
• EPA Substance Registry System: ethyl 3-(4-bromo-2-hydroxyphenyl)-3-oxopropanoate(651780-07-3)

Safety Data

• Hazardous Substances Data: 651780-07-3(Hazardous Substances Data)

Upstream product

• 30186-18-6 4'-bromo-2'-hydroxyacetophenone 
• 105-58-8 Diethyl carbonate 

Downstream Products

• 18735-82-5 7-bromo-4-hydroxy-2H-chromen-2-one 

Relevant articles and documents

Coumarin NEDD8 activating enzyme inhibitor as well as preparation method and application thereof

The invention discloses a coumarin NEDD8 activating enzyme inhibitor in the general formula I as well as pharmaceutically acceptable salts, solvate, polymorphic substances, tautomers, metabolites and prodrugs of the coumarin NEDD8 activating enzyme inhibitor. The invention further discloses an application of the coumarin NEDD8 activating enzyme inhibitor to preparation of anti-tumor drugs and a preparation method of the coumarin NEDD8 activating enzyme inhibitor. Pharmacological results show that the compound has a good effect of resisting tumor cell proliferation and is clinically applicable to preparation of drugs for treating tumors.