651780-27-7

Usage

Uses

Used in Pharmaceutical Synthesis:
Ethyl 6-bromobenzo[d]isoxazole-3-carboxylate is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the molecular structures of various drugs. Its unique chemical properties allow for the development of new therapeutic agents with potential applications in treating a range of medical conditions.
Used in Agrochemical Production:
In the agrochemical industry, ethyl 6-bromobenzo[d]isoxazole-3-carboxylate is used as a building block for the creation of pesticides and other crop protection agents. Its incorporation into these compounds can enhance their effectiveness in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Fine Chemicals Manufacturing:
Ethyl 6-bromobenzo[d]isoxazole-3-carboxylate is utilized as a component in the production of fine chemicals, which are high-purity chemicals used in various applications such as research, diagnostics, and specialty manufacturing. Its presence in these compounds can improve their performance and contribute to the development of innovative products.
Used in Chemical Research:
As a compound with potential biological activity, ethyl 6-bromobenzo[d]isoxazole-3-carboxylate is employed in chemical research to explore its properties and potential applications. Researchers use ethyl 6-bromobenzo[d]isoxazole-3-carboxylate to investigate its interactions with biological systems and to develop new methods for its synthesis and modification, further expanding its utility in various industries.

Upstream product

• 199328-35-3 ethyl 2-(4-bromo-2-nitrophenyl)acetate 
• 875258-18-7 ethyl (4-bromo-3-nitrophenyl)acetate 
• 110-46-3 isopentyl nitrite 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 
• 100487-82-9 4-bromo-2-nitro-benzoic acid methyl ester 

Downstream Products

• 668970-58-9 6-(2-trifluoromethyl-phenyl)-benzo[d]isoxazole-3-carboxylic acid ethyl ester 
• 668970-09-0 ethyl 6-(2-methylphenyl)benzoisoxazole-3-carboxylate 
• 57764-49-5 ethyl 1,2-benzisoxazole-3-carboxylate 
• 1093631-61-8 ethyl 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1,2-benzisoxazole-3-carboxylate 
• 1093632-05-3 ethyl 6-(4-hydroxyphenyl)-1,2-benzisoxazole-3-carboxylate 
• 668970-13-6 1,1-dimethylethyl 2-[(6-bromobenzoisoxazole-3-carbonyl)amino]-5-cyanobenzoate 

Relevant academic research and scientific papers

BENZOISOXAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION

Compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.

COMPOUNDS AND METHODS FOR MODULATING FXR

Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, AND 1,2-BENZISOTHIAZOLES, AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds for example, indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS

Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.

ANTIBACTERIAL BENZOIC ACID DERIVATIVES

The invention provides antimicrobial agents and methods of using the agents for sterilization, sanitation, antisepsis, disinfection, and treatment of infections in mammals.