65195-20-2

Basic information

• Product Name: 2-(1-PIPERIDINO)PHENOL
• Synonyms: 2-(1-PIPERIDINO)PHENOL;2-PIPERIDIN-1-YL-PHENOL;2-PIPERIDINOPHENOL;1-(2-Hydroxyphenyl)piperidine;2-Piperidinophenol,98%;2-(1-Piperidinyl)phenol, 98%
• CAS NO: 65195-20-2
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.24
• Mol File: 65195-20-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 76-77°C
• Boiling Point: 296.8 °C at 760 mmHg
• Flash Point: 145.3 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.000795mmHg at 25°C
• Refractive Index: 1.575
• BRN: 151777
• CAS DataBase Reference: 2-(1-PIPERIDINO)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-PIPERIDINO)PHENOL(65195-20-2)
• EPA Substance Registry System: 2-(1-PIPERIDINO)PHENOL(65195-20-2)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-52-41-37/38-22
• Safety Statements: 26-36-39
• Hazardous Substances Data: 65195-20-2(Hazardous Substances Data)

Usage

Uses

2-(1-Piperidinyl)phenol is used as primary and secondary intermediates.

InChI:InChI=1/C11H15NO/c13-11-7-3-2-6-10(11)12-8-4-1-5-9-12/h2-3,6-7,13H,1,4-5,8-9H2

Upstream product

• 5542-49-4 piperidin-1-yl benzoate 
• 108-95-2 phenol 
• 111-24-0 1,5-dibromo-pentane 
• 78657-14-4 2-(piperidin-1-yl)-4,6-di-tert-butylphenol 
• 5181-06-6 1-(2-methoxy-phenyl)piperidine 

Downstream Products

• 1620294-74-7 tert-butyl ((5-((2-(piperidin-1-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)carbamate 
• 1620294-72-5 1-(2-(allyloxy)phenyl)piperidine 

Relevant articles and documents

Iron-Catalyzed Direct Alkylamination of Phenols with O-Benzoyl-N-alkylhydroxylamines under Mild Conditions

A novel iron-catalyzed direct alkylamination reaction of phenols has been achieved with O-benzoyl-N-alkylhydroxylamines as aminating agents. This protocol provides a facile access to N-alkyl-substituted aminophenols though a radical reaction from phenols. The catalytic direct alkylamination operates at room temperature without the need of any ligands and additives to afford the desired products with excellent regioselectivity and functional group tolerance. (Figure presented.).

Selective Preparations; 34. A Convenient Preparation of 2-Piperidinophenols

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