65205-39-2Relevant academic research and scientific papers
Room-temperature oxidative Suzuki coupling reaction of 1,2,3-triazole N-oxides
Liu, Wei,Yu, Yanyan,Fan, Boyi,Kuang, Chunxiang
, p. 2969 - 2971 (2017/07/10)
This study develops a new efficient pathway for synthesis of 2,4-disubstituted 1,2,3-triazoles through regioselective direct arylation between 2-aryl-1,2,3-triazole N-oxides and Ar-B(OH)2. The reaction proceeds smoothly at room temperature and exhibits good yield and high C5 position selectivity. The possible pathway of oxidative Suzuki coupling is also discussed. This simple methodology can be used to construct 2,4-disubstituted 1,2,3-triazole moiety.
