652146-09-3Relevant academic research and scientific papers
Platinum(II)-catalyzed reaction of γ,δ-ynones with alkenes for the construction of 8-oxabicyclo[3.2.1]octane skeletons: Generation of platinum-containing carbonyl ylides from acyclic precursors
Kusama, Hiroyuki,Ishida, Kento,Funami, Hideaki,Iwasawa, Nobuharu
supporting information; experimental part, p. 4903 - 4905 (2009/02/08)
(Chemical Equation Presented) Two types of bicycles can be prepared selectively by the title reaction, depending on whether or not a substituent is present at the propargylic position of the ynone substrate (see scheme). The cycloaddition of carbonyl ylid
Efficient One-Step Aldol-Type Reaction of Ketones with Acetals and Ketals Mediated by Dibutylboron Triflate/ Diisopropylethyl Amine
Li, Lian-Sheng,Das, Sanjib,Sinha, Subhash C.
, p. 127 - 130 (2007/10/03)
(Equation presented) A highly efficient one-step Mukaiyama aldol-type reaction has been developed for the synthesis of β-alkoxy carbonyl compounds starting from ketones and acetals/ketals. The reaction is mediated by a combination of Bu2BOTf and i-Pr2NEt affording the products in high yields. Formation of the two possible diastereoisomers of the β-alkoxy ketones from the chiral acetals shows that the condensation takes place by an SN1 mechanism, involving prior opening of the acetal to an oxonium ion.
