652146-28-6

Basic information

• Product Name: Cyclohexaneacetic acid, 1-methoxy-alpha-methyl-, methyl ester (9CI)
• Synonyms: Cyclohexaneacetic acid, 1-methoxy-alpha-methyl-, methyl ester (9CI)
• CAS NO: 652146-28-6
• Molecular Formula: C11H20O3
• Molecular Weight: 200.2747
• Product Categories: CYCLOHEXANE;METHOXY
• Mol File: 652146-28-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexaneacetic acid, 1-methoxy-alpha-methyl-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexaneacetic acid, 1-methoxy-alpha-methyl-, methyl ester (9CI)(652146-28-6)
• EPA Substance Registry System: Cyclohexaneacetic acid, 1-methoxy-alpha-methyl-, methyl ester (9CI)(652146-28-6)

Safety Data

• Hazardous Substances Data: 652146-28-6(Hazardous Substances Data)

Upstream product

• 933-40-4 cycloxexanone dimethyl ketal 
• 554-12-1 propanoic acid methyl ester 

Relevant articles and documents

Efficient One-Step Aldol-Type Reaction of Ketones with Acetals and Ketals Mediated by Dibutylboron Triflate/ Diisopropylethyl Amine

(Equation presented) A highly efficient one-step Mukaiyama aldol-type reaction has been developed for the synthesis of β-alkoxy carbonyl compounds starting from ketones and acetals/ketals. The reaction is mediated by a combination of Bu2BOTf and i-Pr2NEt affording the products in high yields. Formation of the two possible diastereoisomers of the β-alkoxy ketones from the chiral acetals shows that the condensation takes place by an SN1 mechanism, involving prior opening of the acetal to an oxonium ion.