652153-65-6Relevant academic research and scientific papers
Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors
Kuo, Gee-Hong,DeAngelis, Alan,Emanuel, Stuart,Wang, Aihua,Zhang, Yan,Connolly, Peter J.,Chen, Xin,Gruninger, Robert H.,Rugg, Catherine,Fuentes-Pesquera, Angel,Middleton, Steven A.,Jolliffe, Linda,Murray, William V.
, p. 4535 - 4546 (2005)
On the basis of previous studies, we identified pyrazine-pyridine A as a potent vascular endothelial growth factor inhibitor and pyrimidine-pyridine B as a moderately potent cyclin dependent kinase (CDK) inhibitor. A proposed combination of CGP-60474 and
SUBSTITUTED TRIAZINE KINASE INHIBITORS
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Page 43-45, (2010/11/30)
The present invention provides substituted 1,3,5-triazine compounds as kinase inhibitors and a method for treating or ameliorating a kinase mediated disorder.
