652155-33-4Relevant academic research and scientific papers
Synthesis, X-ray crystallography and computational studies concerning an oxadiazinone derived from D-camphor: A structural limitation of oxadiazinones as chiral auxiliaries
Squire, Michael D.,Davis, Ryan A.,Chianakas, Karah A.,Ferrence, Gregory M.,Standard, Jean M.,Hitchcock, Shawn R.
, p. 1047 - 1053 (2007/10/03)
A camphor-based oxadiazinone was prepared by reaction of the N-nitroimine of d-camphor with (1R,2S)-norephedrine; the reduction of the resultant imine; N-nitrosation of the amine; reduction to the corresponding hydrazine and cyclization. The conformationa
Intramolecular Chiral Relay at Stereogenic Nitrogen. Synthesis and Application of A New Chiral Auxiliary Derived from (1R,2S)-Norephedrine and Acetone
Hitchcock, Shawn R.,Casper, David M.,Vaughn, Jeremy F.,Finefield, Jennifer M.,Ferrence, Gregory M.,Esken, Joel M.
, p. 714 - 718 (2007/10/03)
(1R,2S)-Norephedrine has been employed in the synthesis of a novel 3,4,5,6-tetrahydro-2H-1,3,4-oxadiazin-2-one via reductive alkylation with acetone, N-nitrosation, reduction, and cyclization. The oxadiazinone was treated with either propionyl chloride or
