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Usage

Uses

Used in Food and Beverage Industry:
Ethylmaltol is utilized as a flavor enhancer for its ability to intensify the sweetness and aroma of various food and beverage products, thereby improving the overall sensory experience for consumers.
Used in Tobacco Products:
In the tobacco industry, ethylmaltol is employed to add a sweeter flavor to tobacco products, enhancing their appeal to users.
Used in E-Liquids for Electronic Cigarettes:
Ethylmaltol is incorporated into e-liquids for electronic cigarettes to create a more palatable and sweeter taste, which can be a determining factor for consumer preference.
Used in Pharmaceutical Industry:
Ethylmaltol has been studied for its potential antioxidant and anti-inflammatory properties, indicating its possible use in the development of pharmaceutical products for health and wellness applications.
Used in Cosmetic Industry:
Due to its potential antioxidant properties, ethylmaltol may also find use in the cosmetic industry, where it could contribute to the development of products aimed at skin health and protection.

InChI:InChI=1/C6H10N2O2/c1-4-5(2-3-9)6(10)8-7-4/h9H,2-3H2,1H3,(H2,7,8,10)

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 

Downstream Products

• 7721-57-5 7-methyl-5,6-diazaspiro[2.4]hept-6-en-4-one 

Relevant academic research and scientific papers

3-pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing

We have previously shown that the higher homologue of (S)-glutamic acid [(S)-Glu], (S)-α-aminoadipic acid [(S)-α-AA] is selectively recognized by the mGlu2 and mGlu6 subtypes of the family of metabotropic glutamic acid (mGlu) receptors. Furthermore, a number of analogues of (S)-α-AA, in which the terminal carboxyl group has been replaced by various bioisosteric groups, such as phosphonic acid or 3-isoxazolol groups, have been shown to interact selectively with different subtypes of mGlu receptors. In this paper we report the synthesis of the 3-pyrazolone bioisosteres of α-AA, compounds (RS)-2-amino-4-(1,2-dihydro-5-methyl-3-oxo-3H-pyrazol-4-yl)butyric acid (1) and (RS)-2-amino-4-(1,2-dihydro-1,5-dimethyl-3-oxo-3H-pyrazol-4-yl)butyric acid (2). At a number of steps in the reaction sequences used, the reactions took unexpected courses and provided products which could not be transformed into the target compounds, and attempts to synthesize the 2,5-dimethyl isomer of 2, compound 3, failed. An X-ray crystallographic analysis of the intermediate 1,2-dihydro-4-(2-hydroxyethyl)-2,5-dimethyl-3H-pyrazol-3-one (5b) confirmed the expected regioselectivity of the reaction between methylhydrazine and α-acetylbutyrolactone (4). Neither 1 nor 2 showed significant effects at the different types of ionotropic glutamic acid receptors or at mGlu(1a) (group I), mGlu2 (group II), and mGlu(4a) and mGlu6 (group III) receptors, representing the three indicated groups of mGlu receptors.