652965-06-5

Upstream product

• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 
• 582313-57-3 4-chloro-7-fluoro-7-deazapurine 
• 452-51-7 D-2-deoxyribose 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 4330-34-1 methyl 3,5-di-O-toluoyl-2-deoxy-D-ribofuranose 
• 22276-95-5 5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Fluorinated pyrrolo[2,3-d]pyrimidine nucleosides: 7- Fluoro-7-deazapurine 2′-deoxyribofuranosides and 2′-deoxy-2′-fluoroarabinofuranosyl derivatives

The syntheses of 7-deaza-7-fluoro-2′-deoxyadenosine (1a), 7-deaza-7-fluoro- 2′-deoxyinosine (3a) and 7-deaza-7-fluoro-2′- deoxyguanosine (3c) as well as of the 2′-deoxy-2′- fluoroarabinofuranosyl derivatives 1b, 3b are described. Starting materials were 6

4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

Provided is 4'-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.

ANTI-VIRAL 7-DEAZA D-NUCLEOSIDES AND USES THEREOF

The present invention relates generally to anti-viral compounds, particularly anti-viral 7-deaza D-nucleosides and analogues, or derivatives thereof. The invention also relates to the use of such compounds to treat or prevent hepatitis B virus (HBV) infec