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Milveterol is a long-acting beta-adrenergic agonist (LABA) that is used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It works by relaxing the muscles in the airways, which helps to open up the airways and make breathing easier.
Used in Pharmaceutical Industry:
Milveterol is used as a medication for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It is administered through an inhaler and is meant to be used on a regular schedule to help prevent symptoms of COPD and asthma.
Used in Respiratory Management:
Milveterol is used as a bronchodilator to relax the muscles in the airways, making it easier for individuals with COPD and asthma to breathe. It is not intended for immediate relief of sudden breathing difficulties, for which a fast-acting inhaler should be used.
Used in Heart Condition Management (with caution):
Milveterol may cause side effects such as increased heart rate, tremors, and nervousness. It is used with caution in individuals with certain heart conditions to manage COPD and asthma symptoms while monitoring for potential cardiac side effects.

652990-07-3

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652990-07-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 652990-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,2,9,9 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 652990-07:
(8*6)+(7*5)+(6*2)+(5*9)+(4*9)+(3*0)+(2*0)+(1*7)=183
183 % 10 = 3
So 652990-07-3 is a valid CAS Registry Number.

652990-07-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-[[(2R)-2-hydroxy-2-phenylethyl]amino]phenyl]ethylamino]ethyl]phenyl]formamide

1.2 Other means of identification

Product number -
Other names Milveterol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:652990-07-3 SDS

652990-07-3Downstream Products

652990-07-3Relevant academic research and scientific papers

A multivalent approach to the discovery of long-acting β2- adrenoceptor agonists for the treatment of asthma and COPD

Jacobsen, John R.,Choi, Seok Ki,Combs, Jesse,Fournier, Eric J.L.,Klein, Uwe,Pfeiffer, Juergen W.,Thomas, G. Roger,Yu, Cecile,Moran, Edmund J.

scheme or table, p. 1213 - 1218 (2012/03/11)

A multivalent approach was applied to the design of long-acting inhaled β2-adrenoceptor agonists. A series of dimeric arylethanolamines based on the short acting β2-adrenoceptor agonist albuterol were prepared, varying the nature and length of the linker between the basic nitrogens. None of the C2-symmetric dimers demonstrated increased potency, however dimer 5j, derived from 4-phenethylamine, was found to have increased binding potency in vitro relative to the parent monomer. Optimization of this structure led to the identification of 22 (milveterol) which demonstrates high potency in vitro and long duration of action in a guinea pig model of bronchoprotection.

CHEMICAL PROCESS AND NEW CRYSTALLINE FORM

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Page/Page column 25-26, (2010/02/14)

The present invention relates to the preparation of a ?2 adrenergic agonist in crystalline salt form. In particular the invention relates to preparation of a crystalline salt of compound (I): in particular a crystalline monohydrochloride salt. The inventi

Crystalline form of beta2 adrenergic receptor agonist

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Page 11, (2008/06/13)

The invention provides a novel β2 adrenergic receptor agonist in crystalline salt form. The invention also provides pharmaceutical compositions comprising the novel β2 adrenergic receptor agonist in crystalline salt form, formulation

CRYSTALLINE β2 ADRENERGIC RECEPTOR AGONIST

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Page/Page column 31, (2010/02/06)

The invention provides a crystalline salt form of a novel β2 adrenergic receptor agonist. The invention also provides pharmaceutical compositions comprising the crystalline form, formulations containing the pharmaceutical compositions, methods of using th

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