652990-08-4Relevant articles and documents
Compounds having beta adrenergic receptor agonist and muscarinic receptor antagonist activity
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Page/Page column 31-32, (2008/06/13)
This invention provides compounds of formula I: wherein R1, R2, R4, R5, R6, R7, R8a, R8b, W, a, b, c and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
CHEMICAL PROCESS AND NEW CRYSTALLINE FORM
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Page/Page column 26-27, (2010/02/14)
The present invention relates to the preparation of a ?2 adrenergic agonist in crystalline salt form. In particular the invention relates to preparation of a crystalline salt of compound (I): in particular a crystalline monohydrochloride salt. The inventi
FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR
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Page/Page column 53-54, (2008/06/13)
The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.