653-12-3Relevant academic research and scientific papers
Room temperature preparation of trifluoroethenylzinc reagent by metalation of the readily available halocarbon HFC-134a and an efficient, economically viable synthesis of 1,2,2-trifluorostyrenes
Raghavanpillai, Anilkumar,Burton, Donald J.
, p. 7083 - 7091 (2007/10/03)
Trifluoroethenylzinc reagent [CF2=CFZnX] was generated from the readily available halocarbon HFC-134a by an in situ metalation-transmetalation procedure at temperatures near to room temperature (15-20 °C). By systematic standardization of the m
A remarkable room temperature preparation of the trifluorovinylzinc reagent from HFC-134a. A cost-effective, high yield synthesis of α,β,β-trifluorostyrenes
Anilkumar,Burton, Donald J
, p. 2731 - 2733 (2007/10/03)
The reaction of LDA (2.0 equiv.) with a THF solution of ZnCl2 (1.0 equiv.) and CF3CFH2 (HFC-134a) (1.2 equiv.) at 15-20°C gives a 73% yield of [F2C=CFZnCl]. Addition of R-C6H4I and Pd(PPhs
