65331-27-3 Usage
Uses
Used in Pharmaceutical Industry:
(8E)-4-phenyl-8-(phenylmethylidene)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione is used as a potential drug candidate for its suggested antioxidant, anti-inflammatory, and anticancer activities. (8E)-4-phenyl-8-(phenylmethylidene)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione's unique molecular structure, which includes a phenylmethylidene group and a thione moiety, makes it a promising candidate for the development of new therapeutic agents.
Used in Research and Development:
In the field of scientific research, (8E)-4-phenyl-8-(phenylmethylidene)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione serves as a subject of study to explore its pharmacological properties and potential applications in medicine. (8E)-4-phenyl-8-(phenylmethylidene)-3,4,5,6,7,8-hexahydroquinazoline-2(1H)-thione's biological activities and mechanisms of action are of particular interest to researchers seeking to understand its therapeutic potential and how it may be harnessed for the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 65331-27-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,3,3 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65331-27:
(7*6)+(6*5)+(5*3)+(4*3)+(3*1)+(2*2)+(1*7)=113
113 % 10 = 3
So 65331-27-3 is a valid CAS Registry Number.
65331-27-3Relevant academic research and scientific papers
An efficient and environmentally friendly procedure for the synthesis of some novel 8-Benzylidene-4-phenyl-3,4,5,6,7,8-hexahydro-1H-quinazolin-2-ones/ thiones using tetrabutylammonium hexatungstate as a reusable heterogeneous catalyst under solvent-free conditions
Ghashang, Majid,Mansoor, Syed Sheik,Aswin, Krishnamoorthy
, p. 3289 - 3294 (2014/01/06)
An efficient method for the preparation of 8-benzylidene-4-phenyl-3,4,5,6, 7,8-hexahydro-1H-quinazolin-2- ones/thiones from the reaction of aromatic aldehydes with cyclohexanone and urea or thiourea in the presence of Tetrabutylammonium hexatungstate, [TBA]2[W6O 19], as an efficient, inexpensive catalyst under thermal and solvent-free conditions has been developed. Good yields, short reaction times, straightforward workup, reusability of the catalyst, and green conditions are the most obvious advantages of this procedure.
