65335-74-2

Upstream product

• 930-68-7 cyclohexenone 
• 766-77-8 Dimethylphenylsilane 
• 104066-67-3 1-(dimethylphenylsilyl)-cyclohex-2-en-1-ol 
• 108-94-1 cyclohexanone 
• 181885-74-5 [2-(methoxymethy)phenyl]phenylsilane 
• 3839-31-4 dimethyl(phenyl)silyllithium 

Downstream Products

• 104108-02-3 (R)-2-[(R)-(Dimethyl-phenyl-silanyloxy)-phenyl-methyl]-cyclohexanone 
• 104108-02-3 (S)-2-[(R)-(Dimethyl-phenyl-silanyloxy)-phenyl-methyl]-cyclohexanone 
• 71444-29-6 2-[hydroxy(4-nitrophenyl)methyl]cyclohexan-1-one 

Relevant academic research and scientific papers

Hydrosilylation of carbonyls over electron-enriched Ni sites of intermetallic compound Ni3Ga heterogeneous catalyst

Nanoparticulate intermetallic compound Ni3Ga supported on SiO2has emerged as a highly efficient catalyst for the hydrosilylation of carbonyls, such as aldehydes and ketones, at room temperature. Formation of electron-enriched Niviaal

Photoinduced Formation of Hybrid Aryl Pd-Radical Species Capable of 1,5-HAT: Selective Catalytic Oxidation of Silyl Ethers into Silyl Enol Ethers

A direct visible light-induced generation of a hybrid aryl Pd-radical species from aryl iodide and Pd(0) is reported to enable an unprecedented (for hybrid Pd-radical species) hydrogen atom-transfer event. This approach allowed for efficient desaturation of readily available silyl ethers into synthetically valuable silyl enols. Moreover, this oxidation reaction proceeds at room temperature without the aid of exogenous photosensitizers or oxidants.

Base-free dehydrogenative coupling of enolizable carbonyl compounds with silanes

A dehydrogenative coupling between enolizable carbonyl compounds and equimolar amounts of triorganosilanes catalyzed by a tethered ruthenium complex with a Ru-S bond is reported. The complex is assumed to fulfill a dual role by activating the Si-H bond to release a silicon electrophile and by abstracting an α-proton from the intermediate silylcarboxonium ion, only liberating dihydrogen as the sole byproduct. Reaction rates are exceedingly high at room temperature with very low loadings of the ruthenium catalyst.

Reduction of α,β-unsaturated ketones with diphenylsilanes bearing several substituents on their phenyl moiety catalyzed by rhodium-phosphine complexes

1,4-Addition product was afforded exclusively by rhodiumphosphine complex-catalyzed hydrosilylation by using 2-cyclohexen-1-one and a dihydrosilane bearing an ether substituent in spite of the fact that dihydrosilanes were believed to give 1,2-addition product selectively. Copyright

Dirhodium(II) tetrakis(perfluorobutyrate)-catalyzed 1,4-hydrosilylation of α,β-unsaturated carbonyl compounds

The use of dirhodium(II) catalysts in the 1,4-hydrosilylation of α,β-unsaturated ketones and aldehydes was explored. Dirhodium(II) tetrakis(perfluorobutyrate), Rh2(pfb)4, proved to be the catalyst of choice for this process, providin

Monophasic and biphasic hydrosilylations of enones and ketones using a fluorous rhodium catalyst that is easily recycled under fluorous-organic liquid-liquid biphasic conditions

Additions of PhMe2SiH to 2-cyclohexen-1-one, 2-cyclopenten-1-one, 4,4-dimethyl-2-cyclohexen-1-one, and cyclohexanone (11) are catalyzed by the rhodium complexes ClRh[P(CH2CH2(CF 2)n-1CF3)s

[Rh(OH)(cod)]2 (cod = 1,5-cyclooctadiene): A highly efficient catalyst for 1,4-hydrosilylation of α,β-unsaturated carbonyl compounds

[Rh(OH)(cod)]2 (cod: 1,5-cyclooctadiene) is found to be a highly efficient catalyst for 1,4-hydrosilylation of α,β-unsaturated carbonyl compounds leading to enolsilanes. The reaction of 2-cyclohexen-1-one with HSiMe(OEt)2 in the pres

Dehydrogenative silylation of ketones catalyzed by diphosphinidenecyclobutene-coordinated platinum(II) complexes

Methylplatinum triflate coordinated with 1,2-diphenyl-3,4-bis[(2,4,6-tri-t-butylphenyl)phosphinidene]cyclobutene serves as a highly selective catalyst for dehydrogenative silylation of ketones with HSiMe2Ph in the presence of pyridine as a co-c

Copper hydride-catalyzed tandem 1,4-reduction/alkylation reactions

Exposure of an enone to a catalytic quantity of [CuH(PPh3)]6 in the presence of one of several silyl hydrides (PhMe2SiH, PMHS, HMe2SiOSiMe2H) leads to conjugate reduction with concomitant formation of the corresponding silyl enol ether. Without isolation, treatment of these intermediates with a Lewis acid at low temperatures in the presence of an aldehyde, or with fluoride ion together with an activated halide, affords good yields of the product of 3-component coupling (3-CC) in a single reaction flask. (C) 2000 Elsevier Science Ltd.

Transition metal catalysis in fluorous media: Extension of a new immobilization principle to biphasic and monophasic rhodium-catalyzed hydrosilylations of ketones and enones

The title protocol utilizes CF3C6F11 solutions of ClRh[P(CH2CH2(CF2)(n-1)CF3)3]3 (n=6, 8; 0.8-0.2 mol%) and toluene (biphasic conditions, 60°C) or hexanes o