65349-67-9

Upstream product

• 65349-64-6 4-[2-(3-chloropropyl)phenyl]-2-butanone 
• 65349-63-5 3-(2-Chloromethylphenyl)-propyl chloride 
• 65349-65-7 4-[2-(3-cyanopropyl)phenyl]-2-butanone 
• 67-56-1 methanol 
• 65349-66-8 4-[2-(3-carboxypropyl)phenyl]-2-butanone 

Downstream Products

• 65349-68-0 4-[2-(2-Hydroxy-3,5-dioxo-cyclopent-1-enylmethyl)-phenyl]-butyric acid 

Relevant academic research and scientific papers

5,6-Benzo analogues of prostaglandin E

Disclosed are prostaglandin analogues having the structural formula, STR1 in which: T is selected from the group consisting of carboxyl, alkoxycarbonyl or cyano; M is selected from the group consisting of carbonyl, R-hydroxymethylene or S-hydroxymethylene; L is selected from the group consisting of methylene or methine, provided L is methine only if J is methine; J is selected from the group consisting of methylene, ethylene, R-hydroxymethylene, S-hydroxymethylene or methine, provided J is methine only if L is methine; W is selected from the group consisting of --CH2 --CH-- or trans --CH=C--; T1 and T2 are attached to adjacent carbon atoms; T1 is selected from the group consisting of hydrogen or phenyl, provided T1 is phenyl only if T2 is lower alkyl; T2 is selected from the group consisting of n-pentyl or lower alkyl, provided T2 is lower alkyl only if T1 is phenyl; Or T1 and T2 are joined together to form an alkylene group of 4 or 6 carbon atoms. Also disclosed are methods for preparing such prostaglandin analogues.

5,6-Benzo analogues or prostaglandin E

Disclosed are prostaglandin analogues having the structural formula, STR1 in which: T is selected from the group consisting of carboxyl, alkoxycarbonyl or cyano; M is selected from the group consisting of carbonyl, R-hydroxymethylene or S-hydroxymethylene; L is selected from the group consisting of methylene or methine, provided L is methine only if J is methine; J is selected from the group consisting of methylene, ethylene, R-hydroxymethylene, S-hydroxymethylene or methine, provided J is methine only if L is methine; W is selected from the group consisting of --CH2 --CH-- or trans --CH=C--; T1 and T2 are attached to adjacent carbon atoms; T1 is selected from the group consisting of hydrogen or phenyl, provided T1 is phenyl only if T2 is lower alkyl; T2 is selected from the group consisting of n-pentyl or lower alkyl, provided T2 is lower alkyl only if T1 is phenyl; Or T1 and T2 are joined together to form an alkylene group of 4 or 6 carbon atoms. Also disclosed are methods for preparing such prostaglandin analogues.