653564-15-9Relevant academic research and scientific papers
Synthesis and biological evaluation of fluorescently labeled epothilone analogs for tubulin binding studies
Ganesh, Thota,Schilling, Jennifer K.,Palakodety, Radha K.,Ravindra, Rudravajhala,Shanker, Natasha,Bane, Susan,Kingston, David G. I.
, p. 9979 - 9984 (2003)
The two fluorescently labeled epothilones 14 and 15 have been synthesized using a modification of Nicolaou's macrolactonization and Stille coupling strategy. The cytotoxicities of the compounds were 6.1 and 2.7 μg/mL, respectively, against the A2870 ovari
