653587-69-0

Basic information

• Product Name: (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl bromide
• CAS NO: 653587-69-0
• Molecular Weight: 358.191
• Mol File: 653587-69-0.mol

Chemical Properties

• CAS DataBase Reference: (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl bromide(653587-69-0)
• EPA Substance Registry System: (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionyl bromide(653587-69-0)

Safety Data

• Hazardous Substances Data: 653587-69-0(Hazardous Substances Data)

Upstream product

• 3588-64-5 (R)-2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionic acid 

Downstream Products

• 653587-59-8 [2-(2-benzyl-2-{2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoylamino]-3-phenyl-propionylamino}-3,3,3-trifluoro-propionylamino)-5-benzyloxycarbonylamino-pentanoylamino]-acetic acid tert-butyl ester 
• 881853-83-4 [5-benzyloxycarbonylamino-2-(2-{2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoylamino]-3-phenyl-propionylamino}-3-methyl-2-trifluoromethyl-butyrylamino)-pentanoylamino]-acetic acid tert-butyl ester 
• 653587-57-6 ((S)-2-{2-Benzyl-2-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3,3,3-trifluoro-propionylamino}-5-benzyloxycarbonylamino-pentanoylamino)-acetic acid tert-butyl ester 
• 653587-60-1 ((S)-2-{2-[(R)-2-((S)-2-Amino-pent-4-enoylamino)-3-phenyl-propionylamino]-2-benzyl-3,3,3-trifluoro-propionylamino}-5-benzyloxycarbonylamino-pentanoylamino)-acetic acid 
• 881853-82-3 ((S)-5-Benzyloxycarbonylamino-2-{2-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyrylamino}-pentanoylamino)-acetic acid tert-butyl ester 
• 653587-61-2 [3-((2S,8S,11R)-8-Allyl-11,14-dibenzyl-3,6,9,12,15-pentaoxo-14-trifluoromethyl-1,4,7,10,13-pentaaza-cyclopentadec-2-yl)-propyl]-carbamic acid benzyl ester 
• 881853-84-5 ((S)-2-{2-[(R)-2-((S)-2-Amino-pent-4-enoylamino)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyrylamino}-5-benzyloxycarbonylamino-pentanoylamino)-acetic acid 
• 881853-85-6 [3-((2S,8S,11R)-8-Allyl-11-benzyl-14-isopropyl-3,6,9,12,15-pentaoxo-14-trifluoromethyl-1,4,7,10,13-pentaaza-cyclopentadec-2-yl)-propyl]-carbamic acid benzyl ester 
• 653587-58-7 {(S)-2-[2-((R)-2-Amino-3-phenyl-propionylamino)-2-benzyl-3,3,3-trifluoro-propionylamino]-5-benzyloxycarbonylamino-pentanoylamino}-acetic acid tert-butyl ester 
• 653587-55-4 2-Benzyl-2-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3,3,3-trifluoro-propionic acid 
• 653587-54-3 2-Benzyl-2-[(R)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3,3,3-trifluoro-propionic acid ethyl ester 
• 881853-81-2 2-[(R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-3-phenyl-propionylamino]-3-methyl-2-trifluoromethyl-butyric acid ethyl ester 

Relevant articles and documents

Incorporation of the unusual Cα-fluoroalkylamino acids into cyclopeptides: Synthesis of arginine-glycine-aspartate (RGD) analogues and study of their conformational and biological behavior

A series of six arginine-glycine-aspartate (RGD) cyclopeptide analogues containing a Cα-di- or trifluoromethylamino acid (α-Dfm or α-TfmAaa) at different positions of the ring were synthesized. All peptides were obtained in two diastereomeric f