653593-74-9Relevant academic research and scientific papers
Ecofriendly synthesis of tetrahydropyrimidine derivatives in aqueous medium under ultrasonic irradiation
Koteswara Rao, Valasani,Hari Babu, Boppudi,Raveendra Babu, Kilaru,Srinivasulu, Doddaga,Naga Raju, Chamarthi
experimental part, p. 3368 - 3376 (2012/09/08)
A simple, efficient, and ecofriendly procedure was developed for the synthesis of 2-substituted 1,4,5,6-tetrahydropyrimidine derivatives catalyzed by N-bromosuccinimide using ultrasonic irradiation in aqueous medium. Prominent advantages of this new method are good yields, aqueous medium, short reaction times, and easy workup procedure. The compounds were characterized by infrared, NMR, liquid chromatography-mass spectrometry, and elemental analyses.
