653598-50-6

Basic information

• Product Name: (S)-1-(2-amino-1-methoxy)ethyl-4-tert-butoxybenzene
• Synonyms: (S)-1-(2-amino-1-methoxy)ethyl-4-tert-butoxybenzene
• CAS NO: 653598-50-6
• Molecular Weight: 223.315
• Mol File: 653598-50-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(2-amino-1-methoxy)ethyl-4-tert-butoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-amino-1-methoxy)ethyl-4-tert-butoxybenzene(653598-50-6)
• EPA Substance Registry System: (S)-1-(2-amino-1-methoxy)ethyl-4-tert-butoxybenzene(653598-50-6)

Safety Data

• Hazardous Substances Data: 653598-50-6(Hazardous Substances Data)

Upstream product

• 653598-49-3 (S)-1-(2-azido-1-methoxy)ethyl-4-tert-butoxybenzene 
• 4074-63-9 1-(4-(tert-butoxy)phenyl)ethan-1-one 
• 99-93-4 4-Hydroxyacetophenone 
• 653598-47-1 (S)-2-bromo-1-(4-tert-butoxy)phenylethanol 
• 653598-48-2 (S)-2-azido-1-(4-tert-butoxy)phenylethanol 
• 653598-46-0 2'-bromo-4-tert-butoxyacetophenone 

Relevant articles and documents

Synthesis, stereochemistry confirmation and biological activity evaluation of a constituent from Isodon excisus

A synthesis and stereochemistry confirmation of a constituent recently isolated from the whole plant Isodon excisus is reported. An enantioselective catalytic boron-mediated reduction of an α-bromoketone was utilized in the key synthetic transformation. The methodology described herein was also used for the synthesis of the natural product's enantiomer and several derivatives. In addition, the compounds were evaluated for inhibitory activity in a caspase induction assay. The natural product was found to be devoid of activity, but several derivatives had moderate inhibitory activity (EC 501 μM).