653605-64-2Relevant academic research and scientific papers
Alkoxycarbonyl-Substituted 3-Trifloxypropene Iminium Salts and Iminium-Substituted Δ2,3-Butenolides: Synthesis and Reactivity toward Nucleophiles
Nikolai, Joachim,Maas, Gerhard
, p. 2679 - 2688 (2003)
Triflic anhydride reacts regioselectively with the ethoxy-carbonyl- substituted enaminones 6a-h to give the novel 3-trifloxypropene iminium salts 7a-d or iminium-substituted Δ2,3-butenolides 8a-d and 9a-d in good yields. Hydride reduction of the iminium salts 7a,b affords new 2-dialkylamino-4-trifloxy-but-3-enoates 13a,b, while mild hydrolysis generates 2-oxo-4-trifloxy-butenoates 14a,b. Butenolides 8b,d, and 9c react with methyl hydrazine to afford 4-dialkylamino-pyridazin-3(2H)-ones 12a-c.
