65371-87-1Relevant academic research and scientific papers
Guidelines for β-lactam synthesis: Glycal protecting groups dictate stereoelectronics and [2+2] cycloaddition kinetics
Grinstaff, Mark W.,Balijepalli, Anant S.,McNeely, James H.,Hamoud, Aladin
, p. 12044 - 12057 (2020/11/10)
The alkene-isocyanate cycloaddition method affords β- lactams from glycals with high regio- and stereoselectivity, but the factors that determine substrate reactivity are poorly understood. Thus, we synthesized a library of 17 electron-rich alkenes (glyca
A simple and convenient method for the synthesis of pyranoid glycals
Zhao, Jinzhong,Wei, Shanqiao,Ma, Xiaofeng,Shao, Huawu
experimental part, p. 168 - 171 (2011/02/26)
A simple, mild, and environmentally benign synthesis procedure of pyranoid glycals is described. In a novel fashion, protected glycopyranosyl bromides undergo the reductive elimination in the presence of zinc in phosphate buffer at room temperature. The pyranoid glycals were obtained in good-to-excellent yields (18 examples).
A direct synthesis of 2-deoxy-2-fluoro-α-D-[6-3H]glucopyranosyl uridine-5′-diphosphate
Stick, Robert V.,Watts, Andrew G.
, p. 327 - 329 (2007/10/03)
The synthesis of 2-deoxy-2-fluoro-α-D[6-3H]glucopyranosyl uridine-5′-diphosphate, with the late introduction of the radiolable, has been achieved from 3,4-di-O-benzyl-2-deoxy-2-fluoro-α-D-glucosyl diphenyl phosphate, by an oxidation-reduction s
THE ALKYLATION AND ACYLATION OF GLYCALS VIA AN INITIALIZING ELECTROCHEMICAL STEP
Fischer, Susanne,Hamann, Carl Heinz
, p. 327 - 340 (2007/10/02)
The method of electrochemically induced formation of ether and ester derivatives of saturated mono- and disaccharides was applied to 1,2-unsaturated monosaccharides (D-glycals).The influence of the supporting electrolyte on the product distribution was investigated by variation of the cation.To provide data for comparison, alkylation was also carried out chemically in the presence of different bases, e.g.LiH and NaH.
