65418-83-9

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 586-75-4 4-chlorobenzoyl chloride 
• 7099-87-8 4-bromophenylglyoxylic acid 
• 934-95-2 1-bromo-4-(iodoethynyl)benzene 
• 201230-82-2 carbon monoxide 
• 589-87-7 1,4-bromoiodobenzene 
• 471-25-0 Propiolic acid 
• 16116-78-2 (4-bromophenyl)(trimethylsilyl)acetylene 
• 861721-94-0 1,3-bis(4-bromophenyl)prop-2-yn-1-ol 

Downstream Products

• 861721-85-9 1-{1-(1,1-dimethylethyl)-3-[4-(oct-7-en-1-yl)phenyl]-3-phenylpropa-1,2-dienyl}-4-(oct-7-en-1-yl)benzene 
• 861721-84-8 1-bromo-4-[3-(4-bromophenyl)-1-(1,1-dimethylethyl)-3-phenylpropa-1,2-dienyl]benzene 
• 861721-95-1 acetic acid 1,3-bis-(4-bromo-phenyl)-1-phenyl-prop-2-ynyl ester 
• 861721-83-7 1,3-bis(4-bromophenyl)-1-phenylprop-2-yn-1-ol 

Relevant academic research and scientific papers

TfOH-Promoted Reaction of 2,4-Diaryl-1,1,1-Trifluorobut-3-yn-2-oles with Arenes: Synthesis of 1,3-diaryl-1-CF3-indenes and versatility of the reaction mechanisms

The TfOH-mediated reactions of 2,4-diaryl-1,1,1-trifluorobut-3-yn-2-oles (CF3-substituted diaryl propargyl alcohols) with arenes in CH2Cl2 afford 1,3-diaryl-1-CF3-indenes in yields up to 84%. This new process for synthesis of such CF3-indenes is complete

A general two-step one-pot synthesis process of ynones from α-keto acids and 1-iodoalkynes

A general two-step one-pot synthesis process of ynones was developed by cycloaddition of α-keto acids and 1-iodoalkynes followed by a ring-opening reaction. Its easy conditions and novel mechanism endowed it with two distinctive advantages: iodine-atom bonded to C(sp2) remained intact and α-keto acids became a part of the triple bonds in ynones.

Sequential palladium catalyzed coupling-cyclocondensation-coupling (C3) four-component synthesis of intensively blue luminescent biarylsubstituted pyrazoles

1-, 3-, and 5-Biarylsubstituted pyrazoles can be efficiently prepared by a microwave-assisted consecutive four-component synthesis based upon a sequential Pd-catalyzed coupling-condensation-coupling (C3), a one-pot sequence which concatenates S

Pd-catalyzed selective carbonylative and non-carbonylative couplings of propiolic acid: One-pot synthesis of diarylalkynones

Diarylalkynones were synthesized from one-pot Pd-catalyzed carbonylative and noncarbonylative coupling reactions of propiolic acid with aryl iodides under a carbon monoxide atmosphere. Aryl iodide (2.0 equiv), propiolic acid (1.0 equiv), Pd(PPh3)2Cl2 (5 mol %), CuCl (10 mol %), Et3N (6.0 equiv), and CO (8 atm) were reacted under optimized conditions in CH3CN at 80 °C for 1 h. This process afforded good yields and functional group tolerance.

Studies on the synthesis of macrocyclic allenes by ring closing metathesis and Doering-Moore-Skattebol reaction

Several efficient synthetic approaches to allenic cyclophanes of the general structure 2/3, which are of interest as chiral ligands or host molecules, are described. The combination of the ruthenium-catalyzed ring-closing metathesis and the Doering-Moore-

Oxidation of aromatic compounds: VII oxidation of symmetrically substituted 1,3-diarylpropynones in the system CF3COOH-CH2Cl2-PbO2. New synthesis method of 1,1,2,2-tetraaroylethenes

Preparative oxidation of 1,3-diarypropynones ArC≡CCOAr in a system CF3COOH-CH2Cl2-PbO2 at 18-20°C within 1.5-25 h results in 1,1,2,2-tetraaroylethenes (ArCO)2C= C(COAr)2 in yields up to 75%. The most easily and efficiently the products form from the substrates where the aryl moiety conjugated with the triple bond contains electron-donating substituents p-MeO, p-Me, and p-t-Bu. On heating with hydrazine 1,1,2,2-tetrakis(4-methoxyphenylcarbonyl)ethene is converted into heterocyclic structures: pyridazine and 2,3,6,7-tetraazanaphthalene derivatives.