65425-11-8Relevant academic research and scientific papers
Cu-Catalyzed Cross-Dehydrogenative Coupling of Heteroaryl C(sp2)-H and Tertiary C(sp3)-H Bonds for the Construction of All-Carbon Triaryl Quaternary Centers
Tang, Zhi,Liu, Zhili,Tong, Zhou,Xu, Zhihui,Au, Chak-Tong,Qiu, Renhua,Kambe, Nobuaki
, p. 5152 - 5156 (2019)
A Cu-catalyzed protocol for cross-dehydrogenative coupling of benzofuranones with quinolines, indoles, carbazoles, and thiophene, which furnishes highly functionalized 3,3-diaryl benzofuranones bearing a three aryl quaternary carbon center at the C3 posit
I2-Mediated Cross-Dehydrogenative Coupling and Amidation of 3-Aryl Benzofuranones with Aryl Amines for the Synthesis of 3,3-Diaryl Indolin-2-ones
Tang, Zhi,Wang, Zhiqing,Peng, Zhihong,Yang, Qinghua,Yin, Shuang-Feng,Qiu, Renhua
, p. 2965 - 2973 (2021/02/27)
We have developed a protocol for efficient synthesis of indolin-2-ones from benzofuranones and aryl amines using iodine as a mediator. A diverse range of benzofuranones and aryl amines undergo cross-dehydrogenative coupling and amidation of 3-aryl benzofuranones for the cascade reaction to generate products in 24-93% yields. This reaction can be easily scaled-up to give an indolin-2-one in a gram scale. Further chemical manipulation of the products enabled useful transformations of the phenol ring including alkylation, arylation, etc.
Catalytic Oxidation of 3-Arylbenzofuran-2(3 H)-ones with PCC-H5IO6: Syntheses of 3-Aryl-3-hydroxy/3-amido-3-arylbenzofuran-2(3 H)-ones
Dhotare, Bhaskar B.,Kumar, Mukesh,Nayak, Sandip K.
, p. 10089 - 10096 (2018/08/03)
A pyridinium chlorochromate (PCC)-mediated facile oxidative dimerization of 3-arylbenzofuran-2-ones at ambient temperature was developed which undergo oxidative cleavage to 3-aryl-3-hydroxy-benzofuran-2-ones with PCC at elevated temperatures. Finally, dir
Some reactions of persistent benzofuranone radicals related to the 'old' diazonamide structure
Magnus, Philip,Venable, Jennifer D.,Shen, Lan,Lynch, Vince
, p. 707 - 710 (2007/10/03)
The benzofuranone dimers 9 and 10/11 readily (ca. 75°C) dissociate to the persistent radicals 16 and 17 respectively, which are stable to, dioxygen. The OMe analog 25 dissociates to form the radical 24, which reacts with dioxygen of TEMPO to give 26.
