65429-75-6Relevant academic research and scientific papers
An efficient and facile multicomponent synthesis of 4,6-diarylpyridine derivatives under solvent-free conditions
El-Sayed, Hassan A.,Ouf, Nabil H.,Moustafa, Ahmed H.
, p. 407 - 412 (2014/02/14)
We present an efficient and facile synthesis of 4,6-diaryl-2-oxo-1,2- dihydropyridine-3-carbonitriles (5a-j) via a four-component system of aromatic aldehydes (1), acetophenones (2), ethyl cyanoacetate (3), and ammonium acetate (4). The short reaction tim
Cascade synthesis of 2-pyridones using acrylamides and ketones
Rai, Sunil K.,Khanam, Shaziya,Khanna, Ranjana S.,Tewari, Ashish K.
, p. 44141 - 44145 (2015/02/02)
Microwave assisted non-catalytic condensation of 2-cyanoacetamide with aromatic aldehydes, and enolate mediated Michael-type addition to acrylamide followed by oxidative cyclization, produce 2-pyridones in good to excellent yield. Unsymmetrical ketones produce two regioisomeric enolates, therefore thermodynamic and kinetic products of butan-2-one and pentan-2-one have been isolated and fully characterized. This journal is
One-pot four component synthesis of 4, 6-disubstituted 3-cyano-2-pyridones in polyethylene glycol
Nalage, Santosh V.,Nikum, Ajay P.,Kalyankar, Mohan B.,Patil, Vijay S.,Patil, Umesh D.,Desale, Kamlesh R.,Patil, Shamkant L.,Bhosale, Sidhanath V.
experimental part, p. 406 - 410 (2011/04/12)
The reaction of ketone, aldehyde, ethyl cyanoacetate and ammonium acetate in polyethylene glycol-600 is reported. The reaction proceeds smoothly in the absence of catalyst to yield 2-Pyridones.
One-pot synthesis of 4,6-diaryl-2-oxo-1,2-dihydropyridine-3-carbonitriles via three-component cyclocondensation under solvent-free conditions
Rong, Liangce,Han, Hongxia,Jiang, Hong,Shi, Daqing,Tu, Shujiang
, p. 217 - 224 (2008/03/17)
An efficient and facile synthesis of 4,6-diaryl-2-oxo-1,2-dihydropyridine- 3-carbonitriles via three-component cyclocondensation from aromatic aldehydes, aromatic ketones, and 2-cyanoacetamide under solvent-free conditions is described. The mild reaction
An efficient and facile procedure for the synthesis of 4,6-diaryl-2(1H)- pyridones under solvent-free conditions
Rong, Liangce,Wang, Haiying,Shi, Jingwen,Yang, Fang,Yao, Hao,Tu, Shuajiang,Shi, Daqing
, p. 1505 - 1508 (2008/09/18)
(Chemical Equation Presented) An efficient and convenient method for the preparation of 4,6-diaryl-2(1H)-pyridones by the one-pot reaction of aromatic aldehydes, aromatic ketones and malononitrile, in the presence of sodium hydroxide under solvent-free co
